In recent years, research on risk factors for liver cancer alcohol and smoking effects on the liver gradually in-depth study, National Cancer Institute in the diet, nutrition and cancer prevention. Had reported that the majority of epidemiological investigations showed that heavy drinking and liver cancer, but there are different views, as most of the lack of other risk factors such as whether the merger HEV infection to control.
Drinking and smoking on the liver effects of that: in most of Europe, North America, with alcohol the main cause of liver cancer, especially the HEV in areas of low, 60% _90% of the liver and alcoholic liver sclerosis related. Alcohol and liver cancer in many regional studies show that alcohol consumption and liver cancer mortality was positively correlated, and the type of wine is also a risk factor for hepatocellular carcinoma, mixed drink wine or liquor is not the risk of drinking wine 7.41 times and 6.5 times, to drink wine mixed chance of liver cancer or non-alcohol drink moderate alcohol 6-10 times, there was statistically significant. Although alcohol is not necessarily the liver carcinogen, but alcohol can be used as HEV, hormones and other risk factors for liver cancer induced by agents, accelerators, have enhanced or promote the carcinogenic effect. Hepatitis history and drinking a synergistic effect on the occurrence of liver cancer, liver cancer and hepatitis may be more significant history of a causative factor, alcohol may be a cofactor in liver cancer, and its supporting mechanisms need further clarify the cancer. In general, excessive, long-term decline in alcohol induced liver detoxification function, nutrient intake reduced, decreased immune function, and by fatty liver, alcoholic hepatitis and cirrhosis of the liver and other evolution, eventually leading to liver cancer. Contact smoking and liver cancer as a significant, though not of alcohol, but studies have shown that hepatitis and liver cancer caused by smoking may increase the risk of drinking. Earlier age and smoking, the greater the risk of liver cancer. In short, the impact of drinking and smoking on the liver, a large and long-term drinking causes alcoholic hepatitis and cirrhosis of the liver, eventually leading to liver cancer is the fact that credible, smoking may also increase the risk of liver cancer, the incidence of mechanisms remain to be elucidated.