Tag Archives: yarbrough

New look at complex head and neck tumor behavior

An increasing number of head and neck cancers are caused by a virus, the human papilloma virus (HPV). Using tissue from HPV-positive and HPV-negative (largely linked to smoking) HNSCC tumors, researchers from institutions around the country referenced The Cancer Genome Atlas to develop a comprehensive assessment of alterations, or oncogenes, that could play a role in how the tumors develop and metastasize, said Wendell Yarbrough, M.D., section chief of otolaryngology at Yale School of Medicine and Clinical Program Leader of the Head & Neck Cancer Program at Smilow Cancer Hospital at Yale-New Haven. “To make the progress we envision with personalized medicine, we first have to understand what’s driving these tumors, and this is one of the first studies to do this,” said Yarbrough, an author on the study. …