Method of HPV screening can be effective in developing countries
Nearly all cases of cervical cancer are believed to be caused by HPV infection. …
Nearly all cases of cervical cancer are believed to be caused by HPV infection. …
In a comparison of the three strategies, Julia C. Gage, Ph.D., M.P.H., of the Division of Cancer Epidemiology and Genetics, National Cancer Institute, Bethesda, MD, and colleagues analyzed data from the Kaiser Permanente Northern California (KPNC) large integrated health delivery system, which screened women age 30-64 since 2003 with both HPV and Pap testing. Data were available through 2012, and over 1 million women were screened at approximately 3-year intervals, with a mean follow-up time of 4.36 years. For each testing strategy, they estimated the cumulative risk of cervical cancer after a negative test result. …
The results of their study are published in the journal Cancer Cell. The research team led by Sloan-Kettering researchers studied a tumor suppressor called Merlin. …
The test, available at the UPMC/UPCI Multidisciplinary Thyroid Center and other diagnostic testing agencies, improved the chances of patients getting the correct initial surgery by 30 percent, according to the study published this month in the Annals of Surgery. “Before this test, about one in five potential thyroid cancer cases couldn’t be diagnosed without an operation to remove a portion of the thyroid,” said lead author Linwah Yip, M.D., assistant professor of surgery in Pitt’s School of Medicine and UPMC surgical oncologist…
Principal investigators and co-leaders of Tulane’s Circadian Cancer Biology Group, Steven Hill and David Blask, along with team members Robert Dauchy and Shulin Xiang, investigated the role of melatonin on the effectiveness of tamoxifen in combating human breast cancer cells implanted in rats. “In the first phase of the study, we kept animals in a daily light/dark cycle of 12 hours of light followed by 12 hours of total darkness (melatonin is elevated during the dark phase) for several weeks,” says Hill…
“Right now, we don’t know who, we don’t know when, and we don’t know why people develop brain tumors,” said Elizabeth M. Wilson, MNA, President and CEO, American Brain Tumor Association. “It’s frustrating for the brain tumor community, and it’s why the American Brain Tumor Association funds research to pursue answers to these questions, and it’s why we host this national conference to provide answers families desperately seek.” At the American Brain Tumor Association (ABTA) annual Patient and Family Conference in Chicago, July 25-26, Jill Barnholtz-Sloan, PhD, Associate Professor, Case Comprehensive Cancer Center, Case Western Reserve University School of Medicine, will be the keynote speaker and provide an update on possible causes and risk factors for brain tumors. As Dr. …
“Most people anticipated that participants who were told that they had a positive screen result would experience increased anxiety and reduced quality of life. …
The findings, published in JAMA Internal Medicine, sought to examine why active surveillance, a management program for low-risk disease, which includes repeat PSAs, prostate exams and biopsies, is underused in this patient population. According to the American Cancer Society, 233,000 new cases of prostate cancer will be diagnosed this year, making it the most common non-skin cancer in men…
Breast cancer patients who are positive for the HER2 gene may be at increased risk for heart damage during chemotherapy, according to a new study published in ecancermedicalscience. Patients with the HER2 gene are often treated with trastuzumab or lapatinib, which interfere with its cancer-causing signals…
PD-L1 is a protein that plays an important role in suppressing immune response, and in cancer, it may allow tumors to evade immune attack. …