Tag Archives: university

Treatment for overactive bladder and irritable bowel syndrome advanced through pioneering research — ScienceDaily

The new study, published in The FASEB Journal, has found that this clock activity in turn regulates the cycle of all cells in the body. The team of researchers also discovered that the local biological clock and its control are weakened in aging bladders, demonstrating the importance of the clock in bladder physiology and aging. While currently much is known about the central biological clock, little is known about the peripheral clocks in the body. This latest research challenges the long-held view that the central clock of the brain controls all the peripheral clocks in other parts of the body and that these in turn control the down-stream receptor molecules which generate specific cell activities, such as contraction, secretion and metabolism…

Sequence of rare kidney cancer reveals unique alterations involving telomerase

The collaboration, a project of the National Institutes of Health’s Cancer Genome Atlas initiative, completed the sequence of chromophobe renal cell carcinoma and published the results today in the journal Cancer Cell. “The Cancer Genome Atlas is a federally funded national effort that has already completed the sequence of many major types of cancer (breast, lung, ovarian, for example), but this project is now branching out to sequence more rare types of cancer,” said Dr. …

Deletion predicts survival in advanced non-small cell lung cancer

The BIM protein can activate the programmed cell death also known as the apoptotic pathway in cells. BIM deletion has been detected in 12.8% of the Asian population but is very rarely observed in the Caucasian population. All NSCLC patients treated with any therapy, targeted or chemotherapeutic, ultimately fail their therapy but at varying times. …

Study identifies protein that helps prevent active tuberculosis in infected patients

The discovery could help doctors identify people who are at the greatest risk for the highly contagious and potentially fatal lung disease, and it could point the way toward new treatment strategies for TB. The study, conducted in partnership with researchers from Harvard University School of Public Health and the University of Michigan School of Medicine, was published in the Aug. 20 online edition of the journal Science Translational Medicine…

Leukemia drug shows promise for skin, breast and other cancers — ScienceDaily

Dasatinib fights leukemia by checking the uncontrolled growth of cancer cells. But when used against other cancer cells, researchers found, the drug employs a different strategy: It causes the cells to clump together, thus preventing them from migrating. Without the ability to migrate, cancer cells cannot metastasize (spread to other parts of the body)…

Antibody research paves way for new, more effective influenza drugs

Influenza is a major global health problem. Annual epidemics of seasonal influenza cause approximately three to five million cases of severe illness, leading to between 250,000 and 500,000 deaths worldwide. In the United States, seasonal influenza epidemics are estimated to account for 3.1 million hospitalization days and an average of $10.4 billion loss in direct medical costs. “It is thus urgent to develop new drugs for fighting influenza infection, which requires an understanding of the virus’s life cycle and its interaction with the host’s immune system,” said Yotam Bar-On, a Hebrew University Ph.D. …