Tag Archives: surveillance

Blacks have less access to cancer specialists, treatment

The study, published online in the Journal of the National Cancer Institute, noted there was no difference in risk of death when black patients received the same treatments, such as chemotherapy and surgery, as non-Hispanic white patients. "Other studies have looked at racial disparities in treatment and still others have focused on racial differences in survival rates of cancer patients, but our research attempted to go further by demonstrating the impact of race-based inequalities in cancer treatment on survival rates of black colorectal cancer patients," said James D. Murphy, MD, MS, assistant professor and chief of the Radiation Oncology Gastrointestinal Tumor Service at UC San Diego Moores Cancer Center. The researchers analyzed data from 11,216 patients over the age of 66 with stage IV colorectal cancer from the Surveillance, Epidemiology, and End Results (SEER)-Medicare database…

Customizing treatments for deadly prostate cancer with tumor genomics

"Men with castration-resistant prostate cancer have abysmal survival rates, typically living an average of two years once hormone therapies fail," says Manish Kohli, M.D., a Mayo Clinic oncologist and principal investigator of the Prostate Cancer Medically Optimized Genome-Enhanced Therapy (PROMOTE) study. Dr. Kohli says the poor prognosis for men with this cancer highlights the need for studies like PROMOTE, which seek to match new targeted drugs with the genomic characteristics of individual patients’ tumors. Several new therapies have recently been approved by the FDA for use in treating castration-resistant prostate cancer, offering new hope for men with this disease. …

HPV vaccination rates alarmingly low among young women in Southern US

The study, published online in the journal Vaccine, examined the association between geographic region and HPV vaccine uptake and completion rates among women ages18-26 in 12 states. It is the first study of its kind to include initiation and completion rates and assess data across multiple years. …

Static killers? Natural killer cell activity can be influenced by phosphorylating a protein in NK cells

Since its discovery in the early 1990s, the protein STAT1 (Signal Transducer and Activator of Transcription 1) has been found to be central in passing signals across immune cells, ensuring that our bodies react quickly and appropriately to threats from viruses or other pathogens. Animals without STAT1 are also prone to develop cancer, suggesting that STAT1 is somehow involved in protection against malignant cells. The STAT1 protein is known to be phosphorylated on at least two positions: phosphorylation of a particular tyrosine (tyr-701) is required for the protein to enter the cell nucleus (where it exerts its effects), while subsequent phosphorylation of a serine residue alters the way it interacts with other proteins, thereby affecting its function. …

Miami face-chewing victim thanks supporters in new video

The homeless man whose face was nearly chewed off by another man in a gruesome attack in Miami last year is recovering well from his severe facial injuries and has expressed gratitude to those who supported him during his recovery process. In a newly added YouTube video from Jackson Health System in Miami, 66-year-old Ronald Poppo is seen sitting on a hospital bed strumming a few chords on a guitar.  He then pauses, holds up the guitar and jokes, “A good enough action shot?” Towards the end of the video, the infamous Miami cannibal attack victim issues a statement to his supporters. “Thanks for contributing and helping out,” Poppo said in the video.  “People in my predicament need to be helped out, and I’m sure there’s other people who also have the same type of predicaments.  I thank the outpouring of people in the community.  I will always be grateful for them.” On May 26, 2012, Poppo was viciously attacked by 31-year-old Rudy Eugene on the MacArthur Causeway in Miami, Fla. Initial reports suggested that Eugene was high on bath salts at the time of the attack, but later toxicology results only indicated the presences of marijuana in his system. Surveillance video from a nearby building shows Eugene pulling Poppo from the shade, stripping and pummeling him before appearing to hunch over and then lie on top of him. A witness described Eugene ripping at Poppo's face with his mouth and growling at a Miami police officer who ordered him to get off the homeless man. The officer then shot and killed Eugene. After the attack, Poppo was taken to Ryder Trauma Center at Jackson Memorial Hospital in Miami, where he underwent months of facial reconstruction to rebuild his features.  Poppo lost both his eyes and his nose in the attack. The Associated Press contributed to this report.source : http://www.foxnews.com/health/2013/05/21/miami-face-chewing-victim-thanks-supporters-in-new-video/

Swine flu found in elephant seals

The H1N1 virus strain that caused a 2009 swine flu outbreak in humans was detected in northern elephant seals off the coast of central California. Scientists say this is the first time marine mammals have been found to carry the H1N1 flu strain, which originated in pigs. The seals seem to have picked up the virus while at sea, but it's unclear how this happened. “We thought we might find influenza viruses, which have been found before in marine mammals, but we did not expect to find pandemic H1N1,” Tracey Goldstein, an associate professor with the UC Davis One Health Institute and Wildlife Health Center, said in a statement. [10 Deadly Diseases That Hopped Across Species] “H1N1 was circulating in humans in 2009,” Goldstein added. “The seals on land in early 2010 tested negative before they went to sea, but when they returned from sea in spring 2010, they tested positive. So the question is where did it come from?” Contact with humans carrying the virus is unlikely when the elephant seals are at sea, because the creatures spend most of their time looking for food in a remote part of the northeast Pacific Ocean off the continental shelf. Exposure could have occurred through feces dumped out of shipping vessels passing through this area. The researchers noted in their report in the journal PLOS ONE this week that H1N1 has been detected in stool samples of hospital patients. Another possible avenue of transmission might have been contact with aquatic birds, thought to be reservoirs for other flu viruses, the researchers say. Goldstein and colleagues tested nasal swabs from more than 900 Pacific marine mammals from 10 different species from Alaska to California between 2009 and 2011. The elephant seals that were studied had been satellite tagged and tracked so that researchers could tell where they had been before and after they were tested for disease. H1N1 was detected in two northern elephant seals within days of their return to land after they went out to sea to forage for a few months. Antibodies to the virus were found in another 28 elephant seals. None of the seals had any signs of illness, which means marine mammals can be infected with zoonotic pathogens but be asymptomatic, the researchers said. The report recommends that people working with and around marine mammals need to take proper biosafety precautions to prevent exposure to diseases that could be quite harmful in humans, even if they don't cause illness in seals. The new research on marine mammals is part of an effort to understand emerging viruses in animals and people by the Centers of Excellence in Influenza Research and Surveillance program, funded by the National Institutes of Health. “The study of influenza virus infections in unusual hosts, such as elephant seals, is likely to provide us with clues to understand the ability of influenza virus to jump from one host to another and initiate pandemics,” Adolfo Garcia-Sastre, a professor of microbiology, said in a statement. Garcia-Sastre directs of the Global Health and Emerging Pathogens Institute at the Icahn School of Medicine, which collaborated with the team from UC Davis on the study. Copyright 2013 LiveScience, a TechMediaNetwork company. All rights reserved. This material may not be published, broadcast, rewritten or redistributed.source : http://www.foxnews.com/health/2013/05/20/swine-flu-found-in-elephant-seals/