Tag Archives: single

Sieving through ‘junk’ DNA reveals disease-causing genetic mutations

The new method designed by the team, described in the journal Science, identified these variants in the under-explored regions of DNA that do not code for proteins, but instead influence activity of other genes. As even more whole genome sequences become available, this approach can be applied to find any potential disease-causing variant in the non-coding regions of the genome…

Vaccinating boys plays key role in HPV prevention

HPV has been linked to anal, penile and certain types of throat cancers in men. Since the virus is also responsible for various cancers in women, vaccinating boys will play a crucial role in reducing cancer rates across the sexes. "HPV is the single most common sexually transmitted infection," says Newman, Canada Research Chair in Health and Social Justice. …

Scientists discover why man stores no fat under skin

British paracyclist Tom Staniford has discovered he is one of just eight people in the world with a rare syndrome. Staniford, 23, is unable to store fat under his skin, losing all the fat around his face and limbs during childhood (despite) having been born a normal weight, the BBC reports. In spite of his wasted frame, Staniford's body thinks he is obese, meaning he has type 2 diabetes. His hearing also became impaired in his childhood, requiring him to wear hearing aids since the age of 10. Staniford’s condition - MDP syndrome - was not identified until recently, when a research team went to work mapping and analyzing his DNA, in a quest to isolate the gene mutation responsible. This was only possible after a second person with the same condition was found. Using the most recent genome sequencing technology, scientists from England, India, Italy and the US were able to identify the single genetic mutation responsible for the rare condition. “All Tom's features can be explained by this one specific change,” said Exeter University scientist Professor Andrew Hattersley, who believes the genetic mutation would have occurred in Staniford’s father’s sperm very early in Staniford's life. Staniford has not let the condition hold him back from achieving several goals, including being British national paracycling circuit race champion in 2011, as well as a degree in law and French. He hopes to become Paralympic circuit race champion at Rio 2016. Staniford does concede, however, that his condition presents particular challenges to training: “I have just 40 percent of the muscles of an average male. I struggle to metabolize sugar and carbohydrates efficiently due to the diabetes - and I struggle to recover due to lack of immediate fuel sources, low testosterone etc. “My muscles have a very narrow margin of efficiency and they're also tight, stiff and inflexible because I don't have fat to perform that role. “This is why I have to constantly experiment and attempt to find, through trial and error, what works.” Staniford is not one to dwell on the rarity of his condition, but says: “[It] is reassuring to know that there are other people with the condition and that we can lead relatively normal lives.” Click for more at news.au.com.source : http://www.foxnews.com/health/2013/06/18/scientists-discover-why-man-stores-no-fat-under-skin/

Diet soda just as harmful to teeth as meth and crack cocaine, study claims

Diet soda may be a popular drink alternative for those looking to cut back on calories, but heavy consumption of these beverages could wreak havoc on a person’s teeth. According to a new study published in the journal General Dentistry, constant exposure to the citric and phosphoric acid in soda – without proper dental hygiene – can be just as damaging to teeth as methamphetamine or crack cocaine, Health Day news reported. “You look at it side-to-side with 'meth mouth' or 'coke mouth,' it is startling to see the intensity and extent of damage more or less the same,” Dr. Mohamed Bassiouny, a professor of restorative dentistry at the Temple University School of Dentistry in Philadelphia, told Health Day News. According to Bassiouny, methamphetamine and crack cocaine are highly acidic, just like diet soda. The study referenced a woman in her 30s who drank 2 liters of diet soda every day for three to five years.   When her teeth were compared to a 29-year-old methamphetamine addict and a 51-year-old crack cocaine user, the levels of tooth rot and decay were very similar.  The woman also admitted she had not seen a dentist in many years. Bassiouny said her teeth had been destroyed by erosion, becoming soft and discolored.  She ultimately had to have all of her teeth removed and replaced with dentures. “None of the teeth affected by erosion were salvageable,” Bassiouny said. Both the meth addict and crack cocaine users had to have all of their teeth removed as well.  According to Health Day News, these drugs also reduce the amount of saliva in the mouth, making it difficult for the acids to wash away. While the results may seem staggering, representatives for the American Beverage Association argue that it’s unlikely soda was the single culprit for the woman’s tooth decay. “The woman referenced in this article did not receive dental health services for more than 20 years -- two-thirds of her life,” the American Beverage Association said in a statement. “To single out diet soda consumption as the unique factor in her tooth decay and erosion -- and to compare it to that from illicit drug use -- is irresponsible.” Click for more from Health Day News.source : http://www.foxnews.com/health/2013/05/29/diet-soda-just-as-harmful-to-teeth-as-meth-and-crack-cocaine-study-claims/