Tag Archives: science

Estrogen is a new weapon against urinary tract infection in postmenopausal women

Urinary tract infections are among the most common diseases, affecting over half of all women at some point in life and repeatedly in 25 percent of these. Menopausal women have an increased risk of recurrent urinary tract infections, which has been associated with low estrogen levels. …

Gene variant may provide novel therapy for several cancer types

This landmark study is published in the June 6, 2013 issue of the journal Science. Ramon Parsons, MD, PhD, Professor and Chair of Oncological Sciences led the team that discovered a mutation in the tumor suppressor gene PTEN, which has subsequently been recognized as the second most common mutation in cancer, especially in breast, prostate, and brain cancers. PTEN encodes a 403 amino acid lipid phosphatase protein that is critical to cellular growth, proliferation, and survival…

Genetic signature of deadly brain cancer identified

"This study identifies a core set of genes and pathways that are dysregulated during both the early and late stages of tumor progression," said University of Rochester Medical Center (URMC) neurologist Steven Goldman, M.D., Ph.D., the senior author of the study and co-director of the Center for Translational Neuromedicine. "By virtue of their marked difference from normal cells, these genes appear to comprise a promising set of targets for therapeutic intervention." As its name implies, gliomas arise from a cell type found in the central nervous system called the glial cell. Gliomas progress in severity over time and ultimately become highly invasive tumors known as glioblastomas, which are difficult to treat and almost invariably fatal. …

Government approves nutritional labels on alcoholic drinks

WASHINGTON – & Alcohol beverages could soon carry nutritional labels like those on food — but only if the producers want to put them there. The Treasury Department, which regulates alcohol, said this week that beer, wine and spirits companies can place labels on packages that include serving size, servings per container, calories, carbohydrates, protein and fat per serving. Such labels have never before been approved. The labels are voluntary, so it will be up to beverage companies to decide whether to use them on their products. The decision is a temporary, first step while the Alcohol and Tobacco Trade and Tax Bureau, or TTB, continues to consider final rules on alcohol labels. Rules proposed in 2007 would have made labels mandatory, but the agency never made the rules final. The labeling regulation issued May 28 comes after a decade of lobbying by hard liquor companies and consumer groups, with clearly different goals: the liquor companies want to advertise low calories and low carbohydrates in their products, while the consumer groups want alcoholic drinks to have the same transparency as packaged foods, which are required to be labeled. “This is actually bringing alcoholic beverages into the modern era,” says Guy Smith, an executive vice president at Diageo, the world's largest distiller and maker of such well-known brands as Johnnie Walker, Smirnoff, Jose Cuervo and Tanqueray. Diageo asked the bureau in 2003 to allow them to add that information to their products as low-carbohydrate diets were gaining in popularity. Almost 10 years later, Smith said he expects Diageo to gradually put the new labels on all of its products, which include a small number of beer and wine companies. “It's something consumers have come to expect,” Smith said. “In time, it's going to be, Why isn't it there?” Not all alcohol companies are expected to use labels, however. Among those who may take a pass: beer companies that don't want consumers counting calories and winemakers that don't want to ruin the sleek look of their bottles. The Wine Institute, which represents more than a thousand California wineries, said in a statement that it supports the ruling but “experience suggests that such information is not a key factor in consumer purchase decisions about wine.” Spokeswoman Gladys Horiuchi said the group knows of no wine companies that plan to use the new labels. The beer industry praised the agency for acknowledging that labels should take into account variations in the concentration of alcohol content in different products. The industry has opposed the idea of defining serving size by fluid ounces of pure alcohol — or as 12 ounces of beer, 5 ounces of wine or 1.5 ounces of 80-proof liquor — on the grounds that you may get more than 1.5 ounces of liquor in a cocktail depending on what else is in the drink and the accuracy of the bartender. The ruling would allow the labels to declare alcohol content as a percentage of alcohol by volume, the approach favored by the beer industry. “We applaud the TTB's conclusion that rules be based on how drinks are actually served and consumed,” said Joe McClain, president of the Beer Institute. McClain said the beer industry is also pleased that the ruling provides “substantial flexibility” in terms of the format and placement of the disclosure on packaging. It is unclear whether beer companies will actually use the labels, however. Consumer advocates criticized the regulation. “It doesn't reflect any concern about public health,” said Michael Jacobson, director of the Center for Science in the Public Interest. “Including fat and carbohydrates on a label could imply that an alcoholic beverage is positively healthful, especially when the drink's alcohol content isn't prominently labeled.” Consumer advocates have also said that listing alcohol content should be mandatory. Jacobson and others support having calorie counts on labels, but they said the labels should not include nutrients that make the alcohol seem more like a food. Current labeling law is complicated. Wines containing 14 percent or more alcohol by volume must list alcohol content. Wines that are 7 to 14 percent alcohol by volume may list alcohol content or put “light” or “table” wine on the label. “Light” beers must list calorie and carbohydrate content only. Liquor must list alcohol content by volume and may also list proof, a measure of alcoholic strength. And wine, beer and liquor manufacturers don't have to list ingredients but must list substances people might be sensitive to, such as sulfites, certain food colorings and aspartame. Tom Hogue of the TTB said the aim of the ruling is to make sure alcohol labeling is more consistent. “The idea here is we are trying to make it easy for the industry to communicate this with consumers if they want to do so, and if their consumers want them to do it,” he said.source : http://www.foxnews.com/health/2013/06/01/government-approves-nutritional-labels-on-alcoholic-drinks/

Biologists take snapshot of fleeting protein process

The biological "freeze-frame" shows the initial step in the formation of actin, a sturdy strand-like filament that is vital for humans. Actin filaments help cells maintain their shape. The filaments, which are called F-actin, also play key roles in muscle contraction, cell division and other critical processes. "One of the major distinctions between cancerous cells and healthy cells is their shape," said study co-author Jianpeng Ma, professor of bioengineering at Rice and the Lodwick T. …