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Database of disease genes shows potential drug therapies

The database was developed by identical twin brothers, Obi Griffith, PhD, and Malachi Griffith, PhD, whose interest in pairing drugs with genes is as much personal as it is scientific. Their mother died of breast cancer 17 years ago, just weeks before their high school graduation. "We wanted to create a comprehensive database that is user-friendly, something along the lines of a Google search engine for disease genes," explained Malachi Griffith, a research instructor in genetics. "As we move toward personalized medicine, there’s a lot of interest in knowing whether drugs can target mutated genes in particular patients or in certain diseases, like breast or lung cancer. …