Tag Archives: king

First detailed picture of cancer-related cell enzyme in action on chromosome unit

Enzymes like PRC1 turn on or turn off the activity of genes in a cell by manipulating individual chromosome units called nucleosomes. “The nucleosome is a key target of the enzymes that conduct genetic processes critical for life,” said Song Tan, professor of biochemistry and molecular biology at Penn State University and the leader of the study’s research team…

Prostate cancer risk reduced by sleeping with many women, but increased with many men, study finds — ScienceDaily

Marie-Elise Parent and Marie-Claude Rousseau, professors at university’s School of Public Health, and their colleague Andrea Spence, published their findings in the journal Cancer Epidemiology. The results were obtained as part of the Montreal study PROtEuS (Prostate Cancer & Environment Study), in which 3,208 men responded to a questionnaire on, amongst other things, their sex lives. Of these men, 1,590 were diagnosed with prostate cancer between September 2005 and August 2009, while 1,618 men were part of the control group. Risk associated with number of partners Overall, men with prostate cancer were twice as likely as others to have a relative with cancer…

Improving breast cancer chemo by testing patient’s tumors in a dish — ScienceDaily

A team of biomedical engineers at Vanderbilt University headed by Assistant Professor Melissa Skala has developed the technique, which uses fluorescence imaging to monitor the response of three-dimensional chunks of tumors removed from patients and exposed to different anti-cancer drugs. In an article published last month by the journal Cancer Research the engineers describe applying the technique to the three major forms of breast cancer. They report that the test can detect significant drops in the metabolic activity levels of all three types of tumors within 72 hours when exposed to an effective drug whereas tumors that were resistant to a drug show no change…

Prostate cancer risk reduced by sleeping with many women, but increased with many men, study finds

Marie-Elise Parent and Marie-Claude Rousseau, professors at university’s School of Public Health, and their colleague Andrea Spence, published their findings in the journal Cancer Epidemiology. The results were obtained as part of the Montreal study PROtEuS (Prostate Cancer & Environment Study), in which 3,208 men responded to a questionnaire on, amongst other things, their sex lives…

Tomosynthesis improves cancer detection in women with dense breast tissue

The study found that adding tomosynthesis (3D mammography) to routine biennial digital mammography screening among U.S. women with dense breasts could improve health outcomes at a reasonable cost relative to digital mammography screening alone. This is the first comparative effectiveness study performed at the national level using an established model, and it could influence future screening recommendations for women with dense breast tissue who comprise nearly half of all women in the United States. “We felt that this analysis would help inform timely policy and practice decisions given both increased attention to screening for women with dense breasts and rapid adoption of tomosynthesis in routine practice,” said Christoph I. …

Improving breast cancer chemo by testing patient’s tumors in a dish

A team of biomedical engineers at Vanderbilt University headed by Assistant Professor Melissa Skala has developed the technique, which uses fluorescence imaging to monitor the response of three-dimensional chunks of tumors removed from patients and exposed to different anti-cancer drugs. In an article published last month by the journal Cancer Research the engineers describe applying the technique to the three major forms of breast cancer. …

A switch to dampen malignancy

“We were trying to identify molecular switches that control the plasticity of epithelial cells,” says Ludwig Oxford director Xin Lu, who led the study with Yajun Guo of The Second Military Medical University in Shanghai, China. “Such plasticity is a hallmark of cancer. In order to metastasize, a settled cancer cell must loosen its structure, wiggle free from its confines, travel to another part of the body and, once there, settle down to form a colony…