Proteins in histone group might influence cancer development, study shows
The findings by researchers at the Ohio State University Comprehensive Cancer Center — Arthur G. James Cancer Hospital and Richard J…
The findings by researchers at the Ohio State University Comprehensive Cancer Center — Arthur G. James Cancer Hospital and Richard J…
The laboratory and animal study also shows how the agent, called SapC-DOPS, targets tumor cells and blood vessels. …
Logic gates are the means by which computers "compute," as sets of them are combined in different ways to enable computers to ultimately perform tasks like addition or subtraction. In DNA computing, these gates are created by combining different strands of DNA, rather than a series of transistors. However, thus far DNA computation events have typically taken place in a test tube, rather than in living cells. NC State chemist Alex Deiters and graduate student James Hemphill wanted to see if a DNA-based logic gate could detect the presence of specific microRNAs in human cells…
The study shows that a protein called Nanog, which is normally active in embryonic stem cells, promotes the growth of cancer stem cells in head and neck cancer. The findings provide information essential for designing novel targeted drugs that might improve the treatment of head and neck cancer. Normally, Nanog helps healthy embryonic stem cells maintain their undifferentiated, uncommitted (i.e., pluripotent) state. …
The physician scientists sought to identify glioblastoma subtype-specific cancer stem cells. Genetic analyses have shown that high-grade gliomas can be divided into four subtypes: proneural, neural, classic and mesenchymal…
There’s a new breed of airport dog. They aren’t looking for drugs or bombs — they are looking for people who need a buddy, a belly to rub or a paw to shake. “His job is to be touched,” volunteer Kyra Hubis said about Henry James, her 5-year-old golden retriever that works a few hours a week at the San Jose airport. “I am just standing there with him. They are talking to him. If I need to answer for him, I do. But I am at the end of his leash, he’s not at the end of mine.” Mineta San Jose International Airport is widely credited with introducing the first airport therapy dog in the days after Sept. 11, 2001, when flights were grounded, passengers were stranded and reaching friends and relatives in the East was nearly impossible. Passengers were anxious and afraid. Enter Orion, owned by a volunteer airport chaplain who got permission to bring the dog to work. He made such a difference that San Jose formalized the program and now has nine dogs. Miami International Airport got onboard the program with one and Los Angeles International Airport has 30 and is hoping to expand its program. The dogs are intended to take the stress out of travel — the crowds, long lines and terrorism concerns. You never know why people are flying, said Heidi Huebner, director of volunteers at LAX, which launched Pets Unstressing Passengers (PUPs) in April. Travelers might be in town for a vacation, a funeral, to visit a sick family member or to attend a business meeting. “You can literally feel the stress levels drop, people start smiling, strangers start talking to each other and everybody walks away feeling really, really good,” Huebner said. Dogs have to be healthy, skilled, stable, well-mannered and able to work on a slack 4-foot leash, said Billie Smith, executive director of Wyoming-based Therapy Dogs, Inc., which certifies the LAX animals. They have to be comfortable with crowds, sounds, smells — and they need to pass through security like all airport workers. Handlers are taught to watch for people who fear or dislike dogs or those who might have allergies. In most cases, people approach the dogs, identifiable by the vests or bandannas they wear. Los Angeles’ dogs, which are featured on trading cards, are as varied as its airport passengers. There’s a long-haired Dalmatian, a Lab-pointer mix, a field spaniel, a poodle, three Australian Labradoodles, a Doberman and a 150-pound Irish wolfhound named Finn who has two tricks. “He looks you in the eye and lays down on the job,” said owner Brian Valente. “When I’m around Finn, it makes me feel like things are OK. When Finn’s around other people, they are OK. It’s almost instant, even if just for a moment,” Valente said. Miami’s sole dog, Casey, a 4-year-old golden retriever, is a star. She has her own website, fan mail, business cards and a role on “Airport 24/7: Miami,” a weekly reality show on the Travel Channel. “Casey is so pure and genuine,” explained Dickie Davis, director of terminal operations and customer service. “She’s not asking for anything or selling anything. She is just a love magnet.” When Claudia McCaskill’s family recently flew home from vacation in Brazil she requested Casey meet the plane to greet her 5-year-old daughter, Carina, who is autistic. She knew Carina would be low on energy and patience and they still had a 2.5-hour drive home to St. Lucie. Casey and handler Liz Miller were there with a gift basket and Carina fell in love with the dog. “Thank you for visiting us at the airport so I would be happy,” Carina said in a video the family made for Casey. Now Carina wants to go back and see Casey again. “I can’t say how much we appreciate what they did for us. It not only helped our daughter, but us too,” McCaskill said. Despite all the smiles, there are also hard moments. Before departing from San Jose, a soldier kneeled down and told Henry James: “OK, buddy, you take care of the house while I am gone,” Hubis said. A woman who said her husband of 40 years told her he wanted a divorce that morning wept on Henry’s shoulder. “He just sat there,” Hubis said. “He knew. He can feel.”source : http://www.foxnews.com/health/2013/06/10/airport-therapy-dogs-take-stress-out-travel/
After the recent loss of their 16-year-old son from testicular cancer, one family is urging other young men to get checked regularly, Gazette Live reported. Michael Rushby from Grangetown, England waited eight long months before telling his brother John on April 17 that he had found a lump on one of his testicles.   “He said he had a problem and showed me one of his testicles,” John told Gazette Live. “The lump was obvious so I took him straight to (the emergency room). The doctor said just by looking at it there was an 80 percent chance it was cancer.” The next day, Michael – known as Mikey by friends and family – was diagnosed with testicular cancer, and doctors discovered that the cancer had also spread to his abdomen and chest. Despite his late diagnosis, Mikey was given a 75 percent chance of survival.  He underwent a week of chemotherapy at Middlesbrough’s James Cook University Hospital and returned home on Friday, April 26.   The following Monday, he was set to return to the hospital for another round of treatments.  But as he was heading downstairs, he lost his strength and collapsed.  He was taken to James Cook, where he died later that day.  It had only been two weeks since he had told his brother about his lump. Now Mikey’s family is speaking out about their son’s death, urging others to get regular health checkups and to not feel ashamed about their medical issues. “I want to say to anyone who ever thinks they might have a problem, go to your mum, go to your dad, go to someone,” Patricia Rushby, Mike’s mom, told Gazette Live. “Mikey could have come to his mum - I wouldn’t have been embarrassed.” “He was my baby. I loved him to pieces,” Patricia said. “I want other young people to know what we have gone through. I wouldn’t want any family to go through what we have.” Click for more from Gazette Live.source : http://www.foxnews.com/health/2013/05/21/after-16-year-old-son-dies-testicular-cancer-mom-urges-others-to-get-checked/
Scientists call this Jekyll-and-Hyde molecule NF-kappa B. In healthy cells, it is a powerful "first responder," a vital part of the body’s immune and inflammatory responses. It spends most of its life in the cell’s cytoplasm, quietly awaiting orders. …