Tag Archives: institut

Chromosomal abnormalities may explain increased cancer risk in type 2 diabetes

Their work was published on July 14, 2013 on the Nature Genetics website. There are more than 200 million diabetics worldwide, and one in three suffer from vascular or nerve complications. In 2012, two studies published in Nature Genetics showed that large chromosomal clonal mosaic events (CMEs)(2) affecting large portions of chromosomes (or even their totality), could be observed in the DNA of blood or saliva cells from some ageing individuals. These studies also suggested that CMEs could predict the risk of cancer, and notably leukemia, in these individuals. …

New method for predicting cancer virulence

This work, published on 22 May 2013 in Science Translational Medicine, suggests that identifying the genes that are abnormally activated in a cancer makes it possible to determine its virulence with great accuracy. This study represents an original concept that will allow cancer patients to be given an accurate diagnosis as well as personalized care. All the cells in our body have the same genes. …