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New viral mutation made middle-aged adults more susceptible to last year’s flu

“We identified a mutation in recent H1N1 strains that allows viruses to avoid immune responses that are present in a large number of middle-aged adults,” said Scott Hensley, Ph.D., a member of Wistar’s Vaccine Center and an assistant professor in the Translational Tumor Immunology program of Wistar’s Cancer Center. Historically, children and the elderly are most susceptible to the severe effects of the influenza viruses, largely because they have weaker immune systems…