Tag Archives: genomics

Genomic study identifies subgroups of breast cancer with varying sensitivities to treatment

The study led by Aleix Prat, Principal Investigator of VHIO´s Translational Genomics Group, in collaboration with José Baselga, Physician-in-Chief of the Memorial Sloan Kettering Cancer Center, New York (USA), has today been published in the journal Clinical Cancer Research. The research centers on the fact that not all HER2+ tumors respond in the same way to anti-HER2 targeted therapy…

Mutations of immune system found in breast cancers

Bernard Friedenson, associate professor of biochemistry and molecular genetics at UIC, looked at the DNA sequences of breast cancers from 21 different women and found mutations in genes involved in immunity in every one of them. The mutations were different in each of the breast cancers he analyzed, but all the mutations would have affected some aspect of pathogen recognition and defense, especially against viruses, Friedenson said. His results are published in the November issue of Functional & Integrative Genomics…