New approach makes cancer cells explode — ScienceDaily
source : http://www.sciencedaily.com/releases/2014/03/140320121906.htm
source : http://www.sciencedaily.com/releases/2014/03/140320121906.htm
source : http://www.sciencedaily.com/releases/2014/03/140312082635.htm
A major new study in the journal Nature sets out the structure of the new family, called glutamate intramembrane proteases – the founding member of which plays a critical role in transforming healthy cells into cancer cells. The research, funded by Cancer Research UK and conducted by scientists at The Institute of Cancer Research, London, defined the structure of a protein called Rce1, and established it as the first known member of a whole new protein family. …
Senior Research Fellow Dr Collin Sones and Professor Rob Eason are working with colleagues from Medicine and the Institute of Life Sciences — Dr Spiros Garbis, Professor Peter Smith and Professor Saul Faust — to develop laser-printed paper-based sensors that can be used to detect biomarkers in cancer patients and see how they are responding to their chemotherapy treatment. …
All information about the human genome is stored in the DNA sequence in the cell nucleus, and was mapped in the early 2000s. …
"We all have a unique composition of hereditary variants of genes that affects how both our body and the tumor react to cancer treatment," Ola Myklebost tells us. He is Professor of Molecular Biology in the Department of Biosciences at the University of Oslo, and also holds a post at the Institute for Cancer Research at Oslo University Hospital. Professor Myklebost has now received a grant of NOK 75 million from the Research Council of Norway to develop the idea for next generation cancer treatment — personalized cancer therapy, directed specifically towards the various mutation faults in cancerous tumors…
Spinal cord injuries sever nerve fibres that conduct signals between the brain and the rest of the body, causing various degrees of paralysis depending on the site and extent of the injury. Functional impairment is often permanent, since the cut nerve fibres do not grow back. The lack of regeneration has been attributed to a blockage from scar tissue that forms at the lesion. …
It is widely accepted that sunscreen stops you from getting burnt but to date there has been academic debate about the effectiveness of sunscreen in preventing skin cancers. Now QUT has undertaken a world-first human study to assess the impact of sunscreen at the molecular level. Researchers found sunscreen provides 100 per cent protection against all three forms of skin cancer: BCC (basal cell carcinoma); SCC (squamous cell carcinoma); and malignant melanoma. …
A multi-disciplinary research team at the University’s Centre for Biomolecular Sciences has uncovered a new way of inhibiting the toxicity and virulence of the notorious superbug, Pseudomonas aeruginosa. This bacteria produces an armoury of virulence factors and is resistant to many conventional antibiotics…
The discovery of the cell death processes that determine the number of ‘regulatory T cells’ an individual has could one day lead to better treatments for immune disorders. Regulatory T cells are members of a group of immune cells called T cells. Most T cells actively respond to clear the body of infections. …