Tag Archives: australia

Teenagers, young adults diagnosed with cancer at increased risk of suicide

A study of nearly eight million Swedes aged 15 and over found that among the 12,669 young people diagnosed with cancer between the age of 15 and 30 there was a 60% increased risk of suicide or attempted suicide. The risk was highest during the first year immediately after diagnosis when suicidal behaviour was 1.5-fold (150%) higher among the cancer patients compared with the cancer-free group. Dr Donghao Lu, a PhD student in the Department of Medical Epidemiology and Biostatistics, Karolinska Institutet (Stockholm, Sweden), said: "We found that there were 22 suicides among the cancer patients versus 14 expected and 136 attempts at suicide versus 80 expected. This equates to an extra 64 instances of suicidal behaviour among the 12,669 young cancer people…

Experimental drug shows promise in lung cancer

The preliminary results of a phase 1B study were presented by Dr. Edward Garon, director of thoracic oncology at UCLA’s Jonsson Comprehensive Cancer Center, on Tuesday October 29 at the 15th World Conference on Lung Cancer. The summit was held by the International Association for the Study of Lung Cancer, in Sydney, Australia…

Measuring segments of genetic material may help predict, monitor recurrence of thyroid cancer

MicroRNAs are copies of very short segments of genetic material that modulate gene expression. Researchers have found that dysregulation of microRNAs may play a role in the development of cancer, and microRNA profiles or "signatures" may be used to classify different types of thyroid tumors. By studying tumor tissue from patients with papillary thyroid cancer, the most common endocrine malignancy, PhD candidate James Lee, MBBS, FRACS, of the Kolling Institute of Medical Research and University of Sydney in Australia, under supervision from Professor Stan Sidhu, and his colleagues found that high levels of two specific microRNAs (microRNA-222 and -146b) within tumors indicated that cancer was more likely to recur after patients’ tumors were surgically removed. …

Clinical trials will improve treatment, follow-up for COPD

"Randomised clinical trials are the best method of obtaining required documentation of the effect, safety and cost-efficacy of various methods or types of treatment employed by the health services," says Kåre Birger Haugen, chair of the programme board of the Research Council of Norway’s Programme on Clinical Research (KLINISKFORSKNING), which has provided funding to the studies. Will follow up COPD patients at home At the Norwegian Centre for Integrated Care and Telemedicine in Tromsø in Northern Norway, researchers will be studying the effect of telemedicine on people suffering from chronic obstructive pulmonary disease (COPD). Telemedicine involves treatment and monitoring activities for patients independent of the location of the medical expertise. …

Two-drug combination improves survival in pancreatic cancer

The new drug is set to become a reference in advanced pancreatic cancer treatment A multicentre phase III study, with centers participating from 11 countries in North America, Europe and Australia, shows that the drug combination nab-paclitaxel and gemcitabine is more effective in the treatment of patients with advanced pancreatic cancer than gemcitabine alone, which has been the standard treatment for these patients up until now. The clinical trial, sponsored by Celgene Corporation, involved 861 patients, half of whom were administered the nab-paclitaxel/gemcitabine combination, while the other half received gemcitabine alone. …

Four genetic variants linked to esophageal cancer and its precursor, Barrett’s esophagus

The findings, by corresponding author Thomas L. Vaughan, M.D., M.P.H., a member of the Epidemiology Program in the Public Health Sciences Division at Fred Hutch, are published online ahead of the December print issue of Nature Genetics. Vaughan co-led the project with co-author David Whiteman, Ph.D., head of the Cancer Control Group at QIMR (formerly known as the Queensland Institute for Medical Research). …

Sunscreen saves superhero gene

It is widely accepted that sunscreen stops you from getting burnt but to date there has been academic debate about the effectiveness of sunscreen in preventing skin cancers. Now QUT has undertaken a world-first human study to assess the impact of sunscreen at the molecular level. Researchers found sunscreen provides 100 per cent protection against all three forms of skin cancer: BCC (basal cell carcinoma); SCC (squamous cell carcinoma); and malignant melanoma. …

New role for Tamoxifen in saving high-risk breast cancer patients

The study involved about 2,500 women from Europe, North America and Australia who have inherited mutations in BRCA1 or BRCA2, the breast cancer susceptibility genes, and who had been diagnosed with breast cancer. About one-third of these women were placed on tamoxifen. Tamoxifen has been used for decades to treat breast cancer and has recently been shown to prevent breast cancers in many women…