What is a tumor biological response modifiers

By | April 18, 2012

What is a tumor biological response modifier, biological response modifier in cancer immunotherapy is based on the formation of the development. Now that the biological response modifier, is able to modify the host directly or indirectly, that the relationship between the tumor, thereby changing the host's biological response of tumor cells, so that is conducive to the host, is not conducive to tumor treatment effect arising from the material or measures. Biological response modifiers that mainly focuses on the relationship between host and tumor, the tumor focus adjustment of antibody response and play a biological anti-tumor effect.
Biological response modifiers includes not only the entire contents immunomodulators, but extends to the cell engineering, genetic engineering, bio-tech fields, as monoclonal antibodies, recombinant cytokines and other endogenous drug clinical application may become the traditional tumor immunity, the modern high-tech immune biology and bio-product of the Trinity. The type of biological response modifiers are many, varied in nature, can be roughly divided into the following clinical types:
What is a tumor biological response modifiers, (1) immunomodulatory agents: immunomodulatory therapy is mainly used to promote, enhance and adjust the body's immune function.
(2) cytokines: such as interferon, interleukin, colony stimulating factor, tumor necrosis factor.
(3) tumor antigen: for specific active immunotherapy, such as tumor vaccines.
(4) effector cells: immunotherapy for the inheritance, such as transfusion LAK cells, TIL cells.
(5) antibody: for passive immunotherapy, such as monoclonal antibodies and their evil guiding therapy eleven conjugate "biological missiles."
(6) tumor of the inhibitory factor: for cancer inhibition and differentiation induction therapy, such as retinoic acid, differentiation factor, maturity and other factors.
What is a tumor biological response modifiers, (7) Other: including bone marrow transplantation, plasma exchange, immunosuppression lift, transfer inhibition, angiogenesis inhibition and so on.

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