Introduction of male urethral cancer

By | April 12, 2012

Introduction of male urethral cancer, urethral cancer is extremely rare in men, 58 years as the incidence peak. Male urethra is generally believed that the local chronic inflammation and cancer, because the majority of patients had gonococcal urethritis, M tract obstruction or repeated dilation of the history of urethral stricture. Inflammation in 24% -26% of cases of malignant lesions in the narrow part of the urethra. However, the relationship between inflammation and cancer is not clear. The initial symptoms of occult cancer is unknown, most believe is a benign stricture, and it is further thought of malignant transformation. The symptoms from the initial to the final diagnosis of the time up to 15 years, an average of 5 months.
(A) of the pathological male urethra in which the tumor site according to the urinary tract epithelial cells from different sources and named prostate transitional cell sites in the past for transitional cell carcinoma, adenocarcinoma of the prostate it was different. Squamous cell carcinoma of the urinary tract starting from the globular membrane distal penile urethra and urethra, urethra, urethral around. Early lesions, urethral cancer, which may be along the urethral sponge and proliferation of blood vessels surrounding tissue. Constant urethral tumor spheroid invasion and deep, such as dirty weeks, the skin of the penis and scrotum, urogenital breast and prostate.
(B) of the prostatic urethra parts of the tumor occurred in the prostatic urethra parts of the tumor as primary transitional cell carcinoma. It must be noted, parts of the prostate transitional cell carcinoma of the urethra and bladder cancer if histologically the same, that the former is the latter part of the urethra caused by the planting. Clinical characteristics of the parts of the lesion without symptoms. In invasive transitional cell carcinoma patients, can be hit hard nodules in the prostate. Most of the patients in this part of the age 60-78 years old. Acid phosphatase levels were normal. The characteristics of the tumor is hormone and radiation therapy is not sensitive. If the lesion invading the prostate membrane, the effect of surgery is poor. Along the surface of tumor growth, treatment with surgery alone, 50% of patients can control the disease. However, most cases of prostate lesions involving the body it is considered to be as radical prostatectomy or cystoprostatectomy and pelvic lymph node dissection.
Introduction of male urethral carcinoma (c) distal urethral cancer, urinary tract epithelial cancer spheroid is the most common urinary tract cancer, men accounted for 75% of urinary tract cancer. 30% of patients in this part of sexual history, history of 35% stenosis, 60% had urethral trauma. The most common symptoms are urinary obstruction (47%), 30% of patients can reach the local masses, 31% of the patients had anterior urethral version of swelling, 20% of the patients had thin tube, 22% of the patients had discharge. Because biopsy is difficult to drawn, diagnosis often is difficult to make, urinary tract X-ray contrast can determine the extent of disease.
(D) of male urethral cancer staging
0: lesions limited to the mucosa (carcinoma in situ).
I: lesions invading the lamina propria, but not over.
II: pathological arrived sponge, but not beyond; or arrival prostate, but not beyond.
III: lesions more than sponge or prostate capsule.
N of A: Local transfer to the groin or pelvic.
N of B: distant metastasis.
Introduction of male urethral carcinoma (e) dealing with non-treated patients the average survival period of 3 months, range 1-15 months. Only 16% of patients survive 5 years.
1. Treatment of distal urethral lesions confined to one half, some of the urine removed from the lesion margins 2cm. Canada had previously used the perineal urethral resection of the penis to a wide range of cases of vomiting disease management, but it will lose the ability to urinate standing after. The survival rate of surgical resection is not higher than some of the penis. When the lesion extended to the scrotum when, III for the penis, testicles, scrotum totally removed.
Introduction of male urethral carcinoma, 2. Treatment of the two urethral mucosa and early cancer can be made by transurethral resection, or the removal of the lesion was made after anastomosis, but very few such operations chance for cure. Distal urethral cancer, penile cancer, dealing with the same principles, the proximal bladder cancer should be Qian prostate or prostatectomy, while for deep lymph node dissection.

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