Characteristics of clear cell adenocarcinoma and diagnosis of 1) Histology, histochemistry, electron microscopy features: clear cell adenocarcinoma subtypes most commonly mixed with other adenocarcinoma. Most cancer cells in solid, partly adenoid structure of cancer cells can also be presented. Translucent cytoplasm, or slightly eosinophilic, see a small amount of mucus; certain nuclear atypia, mitotic figures can be seen. Staining proved that cancer cells contain abundant glycogen and mucus. Cytoplasm rich in electron microscope, glycogen particles and ultrastructural features with the glandular epithelium.
Characteristics of clear cell adenocarcinoma and diagnosis of 2) differential diagnosis: adenocarcinoma of the lung similar to the pulmonary clear cell clear cell carcinoma, squamous cell carcinoma clear cell subtype and similar to other organs occurred in clear cell adenocarcinoma. Therefore, should pay attention to differential diagnosis.
pulmonary clear cell carcinoma: This cancer is the large cell lung carcinoma variant. Cancer in solid structure, cell cytoplasm rich, translucent or eosinophilic, individual cells may contain moving droplets, which is similar to clear cell adenocarcinoma of the lung. Difference between the two: a. clear cell carcinoma of the lung does not contain the light microscope, the morphological characteristics of adenoid structure, and clear cell adenocarcinoma, adenoid structures more easily found; b. clear cell carcinoma of the lung cancer cell cytoplasm occasionally containing small drops like mucus; light microscopy, HE staining difficult to find, and easier to confirm the staining, but the number of cells containing liquid taught less than 5 / 2HPF. Clear cell adenocarcinoma of the lung tissue, cancer cells with more general teaching medium in the HE sub-sections can be identified; c. clear cell carcinoma of the lung necrosis more common than clear cell adenocarcinoma of lung.
lung squamous cell carcinoma of clear cell type: identification of the following: a. clear cell squamous cell carcinoma, clear cell, squamous cell carcinoma of the instrument as part of a squamous cell carcinoma component; clear cell adenocarcinoma, squamous cell carcinoma of the morphological characteristics of the structure, but adenoid cells were arranged in the visible part; b. clear cell adenocarcinoma cells with a larger number Bo fluid, and clear cell carcinoma is occasionally.
Characteristics of clear cell adenocarcinoma and diagnosis of CD Other: lung cancer but also with clear cell renal cell carcinoma, clear cell carcinoma of the liver, clear cell carcinoma, clear cell carcinoma of the breast, thyroid, clear cell adenocarcinoma, clear cell carcinoma of the thyroid and salivary gland and other lung metastasis identification. To learn more about the first to find the primary cancer clinical signs or symptoms.