Physical therapy on patients with cancer the impact of anti-tumor therapy is usually greater the damage, the inevitable damage caused by nutrition and appetite. Whether caused by mechanical and surgical physiological changes, or by chemotherapy or radiation generated by cell level changes in the treatment of cachexia and to be increased in patients with severe nutritional deficiencies in the state.
Surgery is the main treatment of liver cancer, a direct metabolic response to surgery in patients with benign liver disease similar to nitrogen loss and energy needs increase. However, in preoperative patients with liver cancer that tend to have significant weight loss, their ability to cope with tension is weakened, leading to increased morbidity and mortality. Physical trauma, surgery-related pain and the emotional response to endocrine and metabolism can cause a joint response, the purpose of maintaining the body's functions. Hope this time there are several tea gum, glucagon, and cortisol secretion, the results lead to metabolic hyperactivity, weight loss, negative nitrogen balance and water, and sodium retention. Hepatectomy easy to hypoglycemia, hypoproteinemia, fat-soluble vitamin deficiency.
Cancer chemotherapy can profoundly change the nutritional status of patients. Effect may be direct (interference in patients with cellular metabolism or DNA synthesis and cell replication) or indirect (due to nausea, vomiting, altered taste and disgust science diet). Most drugs can stimulate the chemoreceptor trigger zone, resulting in nausea and vomiting. Gastrointestinal mucosa is particularly vulnerable to the rapid conversion of chemical substances to the injury, resulting in stomatitis, ulcers, absorption capacity decreased. These results in turn, caused by intake and nutrient absorption and to further encourage cancer patients to reduce malnutrition.
Radiotherapy effects on the gastrointestinal tract can affect the nutritional status of patients. The severity of injury and radiation dose and irradiated tissue volume. The role of radiation therapy are divided into early and late. Early effect is transient and manifested as diarrhea, bleeding, nausea, vomiting, weight loss, mucositis, dry mouth, taste change and loss of appetite and so on. Late effects include intestinal stenosis, fistula and malabsorption.
Cancer treatment on patients Physique, however, the above situation does not explain the early or middle part of the patient's loss of appetite and weight loss, because the vast majority of patients at this time the tumor is still no clear signs, but also did not receive anti-cancer therapy. Moreover, there are many cancer patients these factors still do not exist, or the impact of these factors is not obvious, they occur cachexia. This shows that the appearance of cachexia must have its deeper causes.