Cause liver and kidney damage adverse drug reactions (1) liver damage. There MTX ,5-FU ,6-MP ,6-TG, FT-207 ,5-DFUR, Ara-C, Cyclo-C, double fluoride cytidine (GEM), PTX, TXT, CBP, Ring sulfur lead (SHP ), ADM, ACM, IDA, DNR, BCNU, CCNU, ACTD, brilliant adriamycin (MTH), CTX, ACNU, FTM, two Australian Euonymus alcohol (DBD), chain gills adriamycin (STZ), NVB, VP- 16, VM-26, L-ASP, CB-1348, PCZ, DTIC, ICRF-159, DDP, AMSA, etc., but most drugs are in a few patients had mild and transient injury. The original poor liver function or high-dose medication, is easy to produce liver injury, treatment should pay attention to close monitoring.
Cause liver and kidney damage adverse drug reactions (2) renal injury. DDP often transient kidney damage, especially in the larger dose, and were not diuretic hydration can cause serious kidney damage. There CBP, SHP, STZ, DNR, aclarubicin (ACM), MMC, BCNU, hole 1e-CCNU, IDA, muscle 1TH, MTX ,6-TG ,5-DFUR, IFO, CTX, L-ASP, DTIC, high-dose BCNU and other renal injury can also occur sometimes, but these drugs are mostly caused by a small number of patients experienced a transient mild injury. Normal renal function, such as the original, and often does not affect the medication, but also to observe the treatment.