Spontaneous cure of rare immune disease
As an adult, the patient contacted NIH’s National Institute of Allergy and Infectious Diseases (NIAID) to evaluate herself and two of her children, who eventually were diagnosed with WHIM syndrome. The patient reported that her symptoms resolved in her 30s, indicating that she had maintained disease remission for nearly 20 years. In their study, NIAID researchers identify chromothripsis, the abrupt fragmentation of a chromosome, as the reason for the cure. …