Targeting cells resistant to chemotherapy — ScienceDaily
source : http://www.sciencedaily.com/releases/2014/04/140424125022.htm
Tag Archives: wellcome-trust
Virus-fighting genes linked to mutations in cancer: Genetic evidence supports role of gene family in cancer development — ScienceDaily
source : http://www.sciencedaily.com/releases/2014/04/140413135912.htm
Discovery of HIV ‘invisibility cloak’ reveals new treatment opportunities
Their study shows how ‘uncloaking’ the virus using an experimental drug triggers an immune response that stops the virus from replicating in cells grown in the laboratory. The findings could lead to new treatments and help to improve existing therapies for HIV infection. The innate immune system is the body’s first line of defence against infection and incorporates an alarm system present in all cells of the body that detects the presence of ‘foreign’ material from invading bacteria and viruses. When the alarm is tripped, the infected cell begins an anti-viral programme and sends out warning signals to alert other cells that a virus is around. …
Cancer’s origins revealed: Genetic imprints and signatures left by DNA-damaging processes that lead to cancer identified
Each mutational process leaves a particular pattern of mutations, an imprint or signature, in the genomes of cancers it has caused. By studying 7,042 genomes of people with the most common forms of cancer, the team uncovered more than 20 signatures of processes that mutate DNA…