‘Junk DNA’ plays active role in cancer progression, researchers find
The researchers, led by Dr Cristina Tufarelli, in the School of Graduate Entry Medicine and Health Sciences, discovered that the presence of this faulty genetic element — known as chimeric transcript LCT13 — is associated with the switching off of a known tumour suppressor gene (known as TFPI-2) whose expression is required to prevent cancer invasion and metastasis. …