Researcher turns sights on prostate cancer, tissue engineering, blood vessel repair — ScienceDaily
source : http://www.sciencedaily.com/releases/2014/01/140130164317.htm
Tag Archives: technology
Scientific first allows doctors to ‘see’ radiation treatment in body
Dartmouth began to investigate a scientific phenomenon called the Cherenkov effect in 2011. Our scientists and engineers theorized that by using Cherenkov emissions the beam of radiation could be "visible" to the treatment team. The ability to capture a beam of radiation would show: • how the radiation signals travel through the body • the dose of radiation to the skin • any errors in dosage…
‘Barcode’ profiling enables analysis of hundreds of tumor marker proteins at once
Minimally invasive techniques — such as fine-needle aspiration or circulating tumor cell analysis — are increasingly employed to track treatment response over time in clinical trials, as such tests can be simple and cheap to perform. …
T-cell research sheds light on why HIV can persist despite treatment
The paper, titled "HIV-1 Persistence in CD4+ T-Cells with Stem Cell-Like Properties," provides evidence that a particular T-cell type may help researchers better understand why HIV can persist despite treatment. Zurakowski’s co-authors include Mathias Lichterfeld, the paper’s lead author, and researchers from Massachusetts General Hospital (MGH); Ragon Institute of MGH, the Massachusetts Institute of Technology and Harvard University; the First Affiliated Hospital of China Medical University; Brigham and Women’s Hospital; and Howard Hughes Medical Institute. Zurakowski explained that HIV treatments do not kill infected cells…
Ultrasound microscopy: Aid for surgeons to make the invisible, visible
Ultrasonic microscopes have a wide range of applications including determining the presence of otherwise invisible defects in components used in the automobile, aeronautical, and construction industries. Professor Naohiro Hozumi of Toyohashi Tech’s Department of Electrical and Electronic Information Engineering is developing the technology to monitor living tissue and cell specimens for medical purposes. …
Potential of protein-measurement technique to standardize quantification of entire human proteome
The study, to be published Dec. 8 online in the journal Nature Methods, shows that the scientists’ targeted protein-detection approach has the potential to systematically and reliably measure the entire human repertoire of proteins, known as the proteome. …
Predicting ovarian cancer survival by counting tumor-attacking immune cells
Scientists at Fred Hutchinson Cancer Research Center have developed a new method for counting a special class of cancer-fighting cells — called tumor-infiltrating T lymphocytes, or TILs — reliably, quickly and cheaply in patients with early stage and advanced ovarian cancer. They describe their findings online Dec. 4 in Science Translational Medicine. …
Cancer-fighting technology progressing well
PNP confirmed that it has completed the first three cohorts of its Phase I clinical trial and is now recruiting for the fourth cohort. The company is looking ahead to Phase II trials and seeking an appropriate partner in the pharmaceutical industry. "We are pleased with the progress made by the product thus far," said William B. Parker, Ph.D., senior research fellow at Southern Research Institute. …
New research to help care for breast cancer patients in their homes
Senior Research Fellow Dr Collin Sones and Professor Rob Eason are working with colleagues from Medicine and the Institute of Life Sciences — Dr Spiros Garbis, Professor Peter Smith and Professor Saul Faust — to develop laser-printed paper-based sensors that can be used to detect biomarkers in cancer patients and see how they are responding to their chemotherapy treatment. …
Early stages breast cancer could soon be diagnosed from blood samples
With a New York University Cancer Institute colleague, the researchers report in an upcoming Clinical Chemistry (now online) that the mixture of free-floating blood proteins created by the enzyme carboxypeptidase N accurately predicted the presence of early-stage breast cancer tissue in mice and in a small population of human patients. "In this paper we link the catalytic activity of carboxypeptidase N to tumor progression in clinical samples from breast cancer patients and a breast cancer animal model," said biomedical engineer Tony Hu, Ph.D., who led the project. "Our results indicate that circulating peptides generated by CPN can serve as clear signatures of early disease onset and progression." The technology is not yet available to the public, and may not be for years. More extensive clinical tests are needed, and those tests are expected to begin in early 2014…