New therapeutic strategy discovered for ovarian cancer
The findings were published online by the journal Nature Medicine. Ovarian cancer is divided into four different histological subtypes. …
The findings were published online by the journal Nature Medicine. Ovarian cancer is divided into four different histological subtypes. …
“Using genetic deletion we found that SIRT1 normally restrains prostatic intraepithelial neoplasia in animals. Therefore too little SIRT1 may be involved in the cellular processes that starts human prostate cancer,” said Dr. Richard Pestell, M.D., Ph.D., MBA, executive Vice President of Thomas Jefferson University and Director of the Sidney Kimmel Cancer Center. “As we had shown that gene therapy based re expression of SIRT1 can block human prostate cancer tumor growth, and SIRT1 is an enzyme which can be targeted, this may be an important new target for prostate cancer prevention.” The researchers led by Dr…
Meditation, yoga, and relaxation with imagery were found to have the strongest evidence supporting their use. They received an “A” grade and are recommended for routine use for anxiety and other mood disorders common to breast cancer patients. …
“Genetic alterations in cancer in humans may involve gene inactivation, amplification or inactivation,” said List.These changes are not present in nonmalignant cells. Common chemotherapeutic agents aggressively kill tumor cells irrespective of genetic alterations.They also have a negative impact on normal cells and can cause significant side effects. …
“This has the potential to dramatically change how we treat cancer,” says Dr. Pramod Srivastava, director of the Carole and Ray Neag Comprehensive Cancer Center at UConn Health and one of the principal investigators on the study. “This research will serve as the basis for the first ever genomics-driven personalized medicine clinical trial in immunotherapy of ovarian cancer, and will begin at UConn Health this fall,” Srivastava says. UConn bioinformatics engineer Ion Mandoiu, associate professor of computer science and engineering, collaborated as the other principal investigator for the study, which has been in development for the past four years…
The report entitled ‘Osteoporosis in men: why change needs to happen’ is released ahead of World Osteoporosis Day on October 20, and highlights that the ability of men to live independent pain-free lives into old age is being seriously compromised. …
Although salivary gland cancer is rare, this retrospective study suggests it occurs 17 times more often in people with inherited mutations in genes called BRCA1 and BRCA2, than those in the general population. “Further study is needed to confirm this preliminary result, but I believe that a BRCA-positive patient with a lump in a salivary gland should have that lesion evaluated as soon as possible,” says co-author Theodoros Teknos, MD, professor and chair of otolaryngology, director of head and neck oncologic surgery, and the David E. Schuller, MD, and Carole H. Schuller Chair in Otolaryngology at the OSUCCC — James. …
The first study, by Rena M. …
“Most of the time, there’s no bad news,” says Karen Rizzo, MD, 2015 president of the Pennsylvania Medical Society and a practicing physician in Lancaster. …
The San Diego-based company has developed an experimental treatment, called ZMapp, which contains antibodies manufactured in plants. …