Protein that keeps people, skeletons organized
In a developing embryo, many bones form based on cartilage templates. The study found that to form these templates, Lkb1 protein controls the progression of immature, dividing cartilage cells into larger, mature and fully differentiated cartilage cells. Without Lkb1, the population of immature cartilage cells disproportionately increases, leading to skeletal tumors. …