Comprehensive list of gene variants developed for cancer cells from nine tissue types
The NCI-60 cancer cell panel represents nine different types of cancer: breast, ovary, prostate, colon, lung, kidney, brain, leukemia, and melanoma. In this study, the investigators sequenced the whole exomes, or DNA coding regions, of each of NCI-60 cell lines, to define novel cancer variants and aberrant patterns of gene expression in tumor cells and to relate such patterns and variants to those that occur during the development of cancer…