‘Signatures’ of genetic mutations in colorectal cancer: Discovery may advance diagnosis, treatment
The technological tour de force, described in the current issue of the journal Nature as the first integrated “proteogenomic” characterization of human cancer, “will enable new advances” in diagnosing and treating the disease, the scientists concluded. “It’s a first-of-its-kind paper. I think it’s a very important advance in the field,” said senior author Daniel Liebler, Ph.D., Ingram Professor of Cancer Research and director of the Jim Ayers Institute for Precancer Detection and Diagnosis at the Vanderbilt-Ingram Cancer Center. The research team, representing Vanderbilt and six other institutions, is part of the Clinical Proteomic Tumor Analysis Consortium (CPTAC), sponsored by the National Cancer Institute of the National Institutes of Health (NIH)…