Protein complex may play role in preventing many forms of cancer
The broad reach of the effect of mutations in the complex, called BAF, rivals that of another well-known tumor suppressor called p53. It also furthers a growing notion that these so-called chromatin-regulatory complexes may function as much more than mere cellular housekeepers. "Although we knew that this complex was likely to play a role in preventing cancer, we didn’t realize how extensive it would be," said postdoctoral scholar Cigall Kadoch, PhD…