An unholy alliance: Colon cancer cells in situ co-opt fibroblasts in surrounding tissue to break out
The question becomes who is invading whom — do cancer cells invade the basement membrane or do some fibroblasts help invading cancers? Researchers at the Institut Curie in Paris now say that they have evidence of a coordinated attack on the basement membrane by cancer cells in situ and CAF cells in the extracellular matrix that begins long before the actual translocation of cancer cells. …