Improved outlook for immune-based therapies: Assay identifies T cells most capable of fighting infections and cancers
Scientists at the Technische Universitaet Muenchen (TUM) have developed the first assay for living T cells that can quantify how strongly the cells’ receptors bind to their targeted antigen. Optimal binding strength or "structural avidity" is thought to be the most important predictor of success in adoptive transfer therapies…