Clues uncovered about how most important tuberculosis drug attacks its target
The antibiotic Pyrazinamide (PZA) has been used to treat TB since the 1950s, but its mechanisms are the least understood of all TB drugs. The PZA findings may help researchers identify new and more effective drugs not only for TB — which can require six months or more of treatment — but other persistent bacterial infections. A report on the research is published online Aug. …