Radiotherapy with chemotherapy, to enhance local tumor control of esophageal cancer and reduce distant metastasis is useful.
Radiotherapy with chemotherapy (1) chemotherapy regimen: a valid choice of esophageal cancer and had radiation sensitizing effect of chemotherapy combined with chemotherapy in the composition, such as cisplatin, fluorouracil and so on.
(2) therapeutic dose and method:
radical radiotherapy: for lesions limited to, non-transfer of patients, usually a total dose of 60-70 Gy (Gy);
palliative radiotherapy: a long lesion or a transfer for patients, generally a total dose of 40-50Gy;
accelerated fractionated radiotherapy: Each radiotherapy 1.5Gy (interval of 6-8 hours), short time to the total.
Esophageal cancer with radiotherapy and chemotherapy (3) Concurrent chemoradiotherapy: esophageal cancer chemotherapeutic agents in fulfilling its role of local and systemic anti-cancer also have increased sensitivity to radiation effects. However, both treatments at the same time, the patient's response to the larger, common side effects and complications of bone marrow suppression, gastrointestinal reactions, radiation esophagitis, bronchitis, esophageal perforation, esophageal fistula. Patients with poor physical fitness can not accept this treatment.
Radiotherapy with chemotherapy, (4) after the first chemotherapy, radiation therapy: This approach can increase the chemotherapy dose and intensity, and reduce the toxicity of the overlap between the two, in which patients easily tolerated.