Lung cancer chemotherapy obvious trauma and toxicity, so that patients can most obvious weakness symptoms and side effects of radiotherapy and chemotherapy-induced symptoms.So, after lung cancer surgery treatment for long-term treatment of patients has important implications. According to the different symptoms in patients with lung cancer after treatment for dialectical treatment of the following methods, and sometimes to receive good results.
After the treatment of lung cancer, small cell lung cancer as a systemic disease, whether surgical or not, are the main systemic chemotherapy (neoadjuvant and adjuvant chemotherapy). Non-small cell lung cancer is also a systemic disease, such as complete resection of pathologic I or H after the 5-year survival of about 60% and 40%, indicating that about 40% r-.-60% of the patients died of tumor within 5 years metastasis or recurrence. Therefore, non-small cell lung cancer according to stage of disease (extent of disease), histological type and degree of differentiation (grade) should be treated with adjuvant therapy after surgery.
Postoperative adjuvant chemotherapy for all small-cell lung cancer. 1A of the complete resection of the principle of non-small cell lung cancer without adjuvant therapy, but for some symptoms, around the tumor vasculature (small blood vessels or lymphatic) have cancer or some unfavorable prognosis (recurrence, metastasis, and survival) changes in the molecular pathology, and the unexplained plasma CEA (carcinoembryonic antigen), SCC (squamous cell antigen) or CYFRA211 still significantly higher in the I of the disease still need to adjuvant therapy. Non-small cell lung cancer (NSCLC) in principle for postoperative radiotherapy, but adjuvant chemotherapy should be done. A dish of resectable after chemotherapy and radiotherapy are required. Adjuvant chemotherapy generally shun uranium-based, joint 20th century drug vinorelbine 90 (NVB), gemcitabine (GEM), such as Taxol or Taxotere. Postoperative chemotherapy should be started after 4 weeks, once every 3-4 weeks, in the absence of special circumstances, for 4 cycles then, because randomized studies have proved that after 4 cycles and more than 4 cycles per significant difference in survival.
Lung cancer after surgery treatment for postoperative residual cancer cells (vascular or bronchial stump) or non-small cell lung cancer patients, in addition to systemic chemotherapy, but should receive local radiation therapy, a combination of both is still yuan fixed mode, but in general surgery received after the first 2 cycles of chemotherapy, then underwent radiotherapy, chemotherapy, radiotherapy after 2-4 cycles, the absence of special circumstances, may be the end of postoperative adjuvant therapy.
Biological therapy after surgery has not been determined, there is no fixed pattern. In theory, the removal or other clinical complete remission after treatment, there may be residual cancer cells hidden in the biological agents such as interferon or anti-interleukin -2 range; tumor cell growth, invasion requires angiogenesis, interferon The main factors for the reduced angiogenesis (vascular endothelial growth factor) activity of one of the factors, it may contain residual tumor cells into tumor formation; or the use of targeted monoclonal antibodies, such as tumor samples (patients or biopsy) or some growth factor receptors in high expression, such as epidermal growth factor-2CcerbB-2) expression of C 2 + -3 +), can be used if the corresponding human monoclonal antibody Herceptin alone or with adjuvant chemotherapy combined, perhaps destroy residual cancer cells. Because cancer development involves many other physiological and pathological processes, whether the type of biological agent or in combination with biological agents which may inhibit some residual cancer cells, are yet to be clinically significant accumulation of long-term observations can still be determined.
Treatment of lung cancer after surgery, Chinese medicine with chemotherapy and radiotherapy at the same time applications, to increase non-specific immune function and improve quality of life have a certain effect, can inhibit the effect of residual cancer cells to be confirmed.