Nausea and vomiting common drugs

By | January 21, 2012

Most anticancer drugs can cause varying degrees of nausea and vomiting, vomiting with the most important of which is along the drug lead (DDP), followed by nitrogen mustard (HNz), cyclophosphamide gaze intently plastic (CTX), ADM, DNR, soft table doxorubicin (EPD, Da Kaba winded (DTIC), actinomycin D (ACTD), CBP, cytarabine (Ara-C), C Kabbah umbilical (PCZ), BCNU, CCNU, VP-16, MTX, slightly Anhui fluorouracil (5-FU), vinblastine (VLB), vincristine (VCR) and so on.
Common occurrence of nausea and vomiting incidence of cases of drug Press
a.90% above the rate. High-dose DDP, HNz, high-dose melphalan (MEL), Da Kaba winded (DTIC), actinomycin D (ACTD).
b.60% -90% incidence. BCNU, CTX, low-dose MTX, VP-16, low doses of DDP. c.30% _60% rate. IFO, DNR, MIT ,5-FU, Ara-C, high-dose MMC, CBP.
d.10% _30% rate. Low-dose MEL, CCNU ,6-MP, low dose MTX, VP-16 (oral), ADM, VLB, low doses of MMC, BLM.
e. 10% less incidence. PTX, VCR, CB-1348.
Common occurrence of nausea and vomiting nausea and vomiting by drugs Start Time
a.1h. HN2 (0.5-2h), ADM (1-2h), ACTD (1-2h), DTIC (1-3h), MMC (1-4h), DDP (1-6h), high dose MTX (1-12h) .
b.2h. BCNU (2-4h), CCNU (2-6h).
c.3h. Large doses of MEL (3-6h) ,5-FU (3-6h), BLM (3-6h), intravenous VP-16 (3-8h).
d.4h. Oral VP-16 (4-6h), DNR (4-6h), MIT (4-6h), CBP (4-6h) ,6-MP (4-8h), VLB (4-8h), VCR (4 -8h), PTX (4-8h), CTX (4-12h), low-dose MTX (4-12h).
e. 48h. CB-1348 (48-72h).
common occurrence of nausea and vomiting drugs by the duration of nausea and vomiting
a. continued within 12h. DNR (6 ten h), MIT (6 ten h), DTIC (1-12h), Ara-C (3-12h), low-dose MTX (3-12h), high-dose MEL (6-12h).
b. 13-24h. CCNU (2-24h), BCNU (4-24h), ACTD (4-20h) ,5-FU (24 + h), VP-16 (24 ten h), HN2 (8-24h), CTX (12 – 24h), CBP (12-24h).
c. 24h or more. DDP (24-72h), high dose MTX (24-72h), MMC (48-72h).

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