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People putting their lives at risk by dismissing cancer symptoms

More than half (53 per cent) of 1,700 people who completed a health questionnaire said they had experienced at least one red-flag cancer ‘alarm’ symptom during the previous three months. But only two per cent of them thought that cancer was a possible cause…

Gene associated with an aggressive breast cancer uncovered

TNBC is deadly because, unlike other types of breast cancers such as estrogen receptor (ER) positive or HER2 amplified breast tumours which have effective targeted therapy, TNBC tumours do not respond to targeted therapy. Breast cancer has many subtypes, each with its own genetic makeup. As such, different subtypes behave differently in invasion and metastasis. …

Scientists deliver a promising one-two punch for lung cancer

Lung cancer, which affects nonsmokers as well as smokers, is the most common cancer worldwide, causing 1.6 million deaths a year, far more than pancreatic, breast and colon cancer combined. About 30 percent of the most common type of lung cancer (non-small) contains a mutation in a gene called KRAS. …

Immune checkpoint inhibitors may work in brain cancers

The novel research shows that brain metastases have dense concentrations of tumour infiltrating lymphocytes, providing an immunoactive environment. Moreover, both primary and secondary brain cancers often exhibit high expression of the immunosuppressive factor programmed cell death ligand 1 (PDL1), which can be inhibited by new treatments, thus activating the immune system. …