A gene normally involved in the regulation of embryonic development can trigger the transition of cells into more mobile types that can spread without regard for the normal biological controls that restrict metastasis, the new study shows. …
The proposed wording of the regulation stipulates ‘explicit and specific patient consent’, meaning that researchers would have to approach patients every single time research is planned in order to consult their data or use tissue samples stored for research purposes. “Hope for patients facing a life-threatening disease like cancer is based on advances in research,” said Kathy Oliver, Chair of the International Brain Tumour Alliance [3]…
"NatA appears essential for the growth of cells and their ability to divide, and we can see elevated production of this enzyme in many forms of cancer" said Ronen Marmorstein, Ph.D., senior author, Hilary Koprowski, M.D. Professor, and leader of The Wistar Institute Cancer Center’s Gene Expression and Regulation program…
Researchers from the Centre for Genomic Regulation led by Miguel Beato have, in an article published in the journal Cell Reports, just revealed that one of these molecules (PLK1 kinase), up to now thought to be related to cancer, can also be crucial for the proper functioning of the cell. PLK1 had always been associated with breast cancer due to its role in cell division. …