The research is described in a paper published online September 18, 2014, in Immunity, a Cell Press journal. Myeloid-derived suppressor cells (MDSCs) are involved in cancer, inflammation and infection. …
"Because the assembly of cells is like an elaborate tinker toy set in which the parts can be used in different combinations to serve various roles, E6AP normally functions in nerve cells to direct brain development and in a functionally related process termed neuronal plasticity which allows nerve cells to alter their patterns of communication with neighboring cells during learning," notes Arthur Haas, PhD, the Roland Coulson Professor and Chairman of Biochemistry and Molecular Biology at LSU Health Sciences Center New Orleans and Director of the laboratory in which the work was performed. The research team included lead investigator Dr. Virginia Ronchi, a postdoctoral fellow, and her colleagues, Jennifer Klein and Dr. Daniel Edwards, all of whom work in Dr…