This molecule is based on a natural protein present in human breast milk, which has been found to have strong and wide-ranging tumour killing properties when bound to certain lipids. Lipids are organic molecules like amino acids and carbohydrates, made up of carbon and hydrogen, and help to store energy and to form biological membranes. …
Grapefruits have long been known for their health benefits, and the subtropical fruit may revolutionize how medical therapies like anti-cancer drugs are delivered to specific tumor cells. University of Louisville researchers have uncovered how to create nanoparticles using natural lipids derived from grapefruit, and have discovered how to use them as drug delivery vehicles. UofL scientists Huang-Ge Zhang, D.V.M., Ph.D., Qilong Wang, Ph.D., and their team today (May 21, 2013), published their findings in Nature Communications. …
The recent turn of events with the Obama Administration and a lack of transparency are a significant red flag to the impending catastrophe of how the proposed changes under the Affordable Care Act could be the next ensuing disaster. 1. Is the IRS capable of fairly enforcing penalties? A major part of the Affordable Care Act is providing insurance for those who don’t have it, or can’t afford it.  The assumption, originally, was that savings would be obtained by coaxing individuals to buy insurance sooner, and prevent the rising cost of catastrophic illness. The hope was that individuals would feel the pain of a financial penalty, enforced by the IRS, and hence opt-in for insurance as opposed to paying the fine.   But recent events, and the follies of the IRS, in using their authority to overstep the boundaries of fairness and jurisdiction, should cause concern.  How effective and unbiased can the IRS truly be in accurately indentifying those individuals who have not complied with the law and enforcing the penalties? …
By altering a very specific step in gene regulation, this compound essentially re-educates cancer cells into normal cells that die as scheduled. One way that cancer cells thrive is by inhibiting a process that would cause them to die on a regular cycle that is subject to strict programming. This study in cells, led by Ohio State University researchers, found that a compound in certain plant-based foods, called apigenin, could stop breast cancer cells from inhibiting their own death. Much of what is known about the health benefits of nutrients is based on epidemiological studies that show strong positive relationships between eating specific foods and better health outcomes, especially reduced heart disease…
Cervical cancer incidence and mortality are markedly higher for low-income and minority women due to higher rates of HPV and limited access to screening and treatment. Vaccination for HPV has the potential to reduce health care disparities in cervical cancer rates if girls are vaccinated prior to sexual experimentation. Although providers felt that parents wanted to prevent cervical cancer in their daughters, some had concerns about safety of the vaccine and promoting early or unsafe sexual activity. …
The discovery of these genetic variations — chromosomal "typos," so to speak — could ultimately help researchers better understand which men are at high risk and allow for early detection or prevention of the disease. "As we continue to cast a wider net, we identify additional genetic risk factors, which point to new mechanisms for disease," said Katherine L. Nathanson, MD, associate professor in the division of Translational Medicine and Human Genetics within the department of Medicine. …
The number of some cancers related to the human papillomavirus (HPV) increased throughout the U.S. before vaccines against the sexually transmitted infection were available, says to a new study. Researchers found an increase in many early-stage cancers and anal and head and neck late-stage cancers across the U.S. …
CU-Boulder Professor Min Han said the research team was interested in how a common tumor suppressor gene known as Retinoblastoma 1, or Rb, behaved under conditions of starvation. The question is important, said Han, because it may help researchers understand why many cancer cells are more susceptible to starvation or fasting than ordinary cells. Han and his team studied a popular lab organism called C. elegans, a translucent nematode smaller than an eyelash…
The protein, called TR4 (testicular orphan nuclear receptor 4), is one of the human body’s 48 nuclear receptors, a class of proteins found in cells that are responsible for sensing hormones and, in response, regulating the expression of specific genes. Using a genome scan, the Salk team discovered that TR4 regulates a gene that produces adrenocorticotropic hormone (ACTH), which is overproduced by pituitary tumors in Cushing’s disease (CD). …