Type of colon cancer chemotherapy

By | January 3, 2012

Results cancer chemotherapy, the type of colon cancer is a common digestive tract cancer, a good site for the rectum and sigmoid colon and rectal junction, have mostly middle-aged patients with colon cancer, colon cancer with clinical manifestations of which the size of the lesion location and pathology type is different. Many patients with early colon cancer can be no clinical symptoms, but with the course of development and growing lesions, can produce a range of common symptoms of colon cancer, such as increased stool frequency, stool and mucus, abdominal pain, diarrhea or constipation, intestinal obstruction, and generalized weakness, weight loss and anemia and other symptoms.
Type of colon cancer chemotherapy (1) the intestine chemotherapy: is laparotomy, the tumor away from the ends of about 8 – lO cm cerclage intestine, and then with 5 – fluorouracil 30 mg / kg body weight, injected into normal saline 50 ml intestine where the tumor after 30 minutes by conventional surgery can improve the 3, 5 and 8 years of survival.
Type of colon cancer chemotherapy (2) arterial infusion chemotherapy: malignant arterial infusion chemotherapy is an important means of comprehensive treatment. Selective arterial infusion chemotherapy is accurate and targeted drug delivery, so that high concentrations of anti-cancer drugs focus on the local tumor, effectively killing cancer cells, improve the therapeutic effect of surgery, clinical symptoms improved significantly, adverse reactions, the method is simple, safe .
Type of colon cancer chemotherapy (3) portal vein infusion chemotherapy: Colorectal cancer in primary tumors after treatment of liver metastasis were 50%. For the prevention of postoperative liver metastasis, portal vein infusion of 5 – fluorouracil, better effect. But their clinical value needs to be further confirmed.
Type of colon cancer chemotherapy (4) intraperitoneal chemotherapy: Colorectal cancer surgery squeeze, cut off when the lymphatic and blood vessels, has the potential to shed cancer cells into the abdominal cavity or cause an already disseminated cancer cells in the peritoneum of the formation of the naked eye can not see the small lesions. Intraperitoneal chemotherapy, can directly increase the concentration of intra-abdominal cancer drugs to enhance the cytotoxicity of local lesions, reduce systemic adverse reactions. But the most effective chemotherapy drugs and a variety of dosage and concentration to be studied further.
Type of colon cancer chemotherapy (5) within lymphoid chemotherapy: colon cancer lymph node metastasis is considered one of the most important ways. Traditional intravenous chemotherapy, the lymphatic system due to low drug concentrations can not solve the problem of lymph node metastasis, lymphatic chemotherapy can only be achieved within the lymphoid tissues of effective drug concentration and improve the effect of chemotherapy. Usually in the colon mucosa or foci endoscopic injection of drugs; Intraoperative intestinal serosa and foci in order to improve the efficacy of drug injection.

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