Nasopharyngeal carcinoma

By | January 21, 2012

NPC is the top place in the nasopharynx and lateral wall of the cancer, age at onset increased rapidly from30years of age,50 to 59age group reached a peak, the male is about2 to 4times the female.
Nasopharyngeal carcinoma are the following:
(1) nasopharyngeal carcinoma radiotherapy: As many as a poorly differentiated nasopharyngeal squamous carcinoma, the preferred radiotherapy.According to extent of disease in patients with systemic conditions and given different doses of radiation.Local implantation of radiation particles can also carry out brachytherapy, has achieved very good results.
(2)Photodynamic therapy: local recurrence after surgery or radiotherapy 1 month after the still residual nasopharyngeal lesions, photodynamic therapy can be used.
      (3)Surgery: Surgical treatment of lesions only by the limitations of the nasopharynx after radiotherapy does not go away, or relapse, or neck lymph nodes are not dissipated by the radiotherapy, and the nasopharynx, has been controlled by the primary tumor.Cervical lymph node metastasis of cervical lymph node dissection should be performed.
(4)is a supplementary chemotherapy or palliative treatment, mainly used in advanced cases, and recurrence after radiotherapy who failed to control.Local implantation of chemotherapy can be particles, or simultaneously with radiotherapy particle implantation, to concurrent radiotherapy and chemotherapy aim has been achieved very good results.Nasopharyngeal lesions may be chemotherapy or interventional arterial chemoembolization.
(5)thermal ablation treatment: such as laser, microwave, radio frequency, argon, etc., using high temperatures to remove lesions with light wounds, the advantages of quick recovery.
(6) Cryotherapy: CO2or liquid nitrogen, etc. can be used to destroy tumor cells frozen to eliminate the lesions.
(7), nasopharyngeal carcinoma gene therapy: Recombinant adenovirusp53gene (trade name: Gendicine) treatment has achieved initial success.Can be carried out before and after local injection of gene drug chemotherapy and radiotherapy, and better efficacy.
Typical cases of nasopharyngeal carcinoma:
Mr. Zhou, 37, the main reason, "ear pain, headachemorethan3years, increasedinJanuary" was hospitalized in September 2005.Back inJune2002 there were incentives for the left ear pain element, and conscious of water left ear channel sound to the hospital diagnosed as "NPC" biopsy report as poorly differentiated squamous cell carcinoma.In the same year in July-line radiation therapy, dose 70Gy, 45 times, symptoms were relieved, not line chemotherapy.1year after the dizziness, the hospital and diagnosed with recurrent nasopharyngeal carcinoma and skull base invasion, the lineXknife treatment, followed by the line of systemic chemotherapy, have used cisplatin, paclitaxel and so on.Later, back pain patients, radionuclide bone scan-line diagnosis for the first5thoracic metastasis, and found multiple lung metastasis, no further radiotherapy.January prior to admission, headache, dizziness increased, review of primary nasopharyngealCTshowed disease progression.
1First, systemic chemotherapy after admission, while giving the drugs and ultrasound conductivity rose white rose white treatment, after1week in stable condition, giving the photodynamic therapy of nasopharyngeal carcinoma.2Photosensitizer intravenously priortwodays, and dark.Seen in the right posterior endoscopic mucosal hypertrophy in congestive pharyngeal recess, eustachian tube occlusion of the right.The optical fiber inserted into the hole from the date of biopsy for crypts, the laser irradiation.12031 day, 20 minutes, and even according tothreedays to clean up after the local surface necrotic material, visible mucosal congestion and edema, the right has been expanded over the previous eustachian tube opening.Conscious patients with headache, nasal symptoms ease than before.2weeks after discharge to dark.2months after the patients symptoms markedly improved, check the right pharyngeal recess stalk membrane edema, right side of the eustachian tube opening to expand, the proposed1Patient to continue chemotherapy, with the anti-1 and a half years in a stable condition.

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