Cancer chemotherapy

By | April 27, 2012

Cancer chemotherapy drugs, diagnosis and treatment of cervical cancer norms that sub cervical squamous cell carcinoma of chemical treatment can be used:
(1) FACA program: 5-FU, ADM, CTX, VCR combination. 5-FU500mg /, the first 1-8 days of intravenous infusion, ADM 45mg / m2, intravenously on day 1, CTX 100mg /, the first 1_14 days of oral, VCR 1. 4mg / time, 1 and 8 days of intravenous , every 4 weeks for a course of treatment.
(2) ACAT programs: ADM, DDP, consumer card mustard (AT-1258) combination therapy. ADM 40mg / m2, day 1 intravenous injection, DDP 50mg / when the intravenous infusion on day 1, AT-1258 40mg, 1, 3, 5 days intravenously every 3 weeks as a course of treatment.
(3) PVB solution: DDP, BLM, VCR combination. DDP 50mg / when the day 1 infusion, BLM 20mg, the first day of intravenous 1_3, VCR 1mg /, the first 1 yao intravenous infusion every 3 weeks as a course of treatment.
Cervical cancer , there are two options:
(1) MFP program: MMC, 5-FU, DDP combination therapy.
MMC 4_6mg, 1, 5 days intravenous, 5-FU 750mg, No. 1_5 days of intravenous infusion, DDP 50mg / when the intravenous drip on day 1 every 3 weeks as a course of treatment.
(2) CAM program: DDP, ADM, MTX combination therapy. DDP 60mg / m2, day 1 infusion, ADM50mg, day 1 intravenous injection, MTX 30mg / when the intravenous drip on day 1 every 3 weeks as a course of treatment. Indications: solid b cervical cancer, local tumor huge clumps associated with parametrial invasion or histological grade in 3 or more, can be used with chemotherapy, radiotherapy; health "of cervical cancer, surgery was found in Confucianism artery bifurcation more lymph node metastasis, cervical cancer radiotherapy or postoperative recurrence or metastasis, and advanced cervical cancer, are the range of chemotherapy. but for the improved survival, Li Shumin had radiation therapy and chemotherapy application of the comprehensive treatment, but not improved treatment.
Contraindications: Bone marrow aplasia, cachexia, and the brain, heart, liver, kidney with severe lesions. Attachment: cervical intraepithelial neoplasia (CIN) in 15% of the overall treatment of CIN can develop into cervical cancer, CIN is difficult to predict the outcome of each case, they have the further risk of malignant development, such as the CINI, CINII and CINill development the risk of cancer were 115%, 30% and 45%. Although some lucky untreated spontaneous regression or disease can be reversed, but in terms of each patient is difficult to estimate and should not feel luck. In any case, CIN development of invasive cancer 7 times the normal situation, which is to be of great importance to and properly handle CIN reasons.
Cancer chemotherapy drugs, CINI: in CIN I patients, 65% of the lesions can be self-limiting; 20% of the lesions persist, remain the same; only 15% of the lesions continue to develop. This is the 15% of patients can not be predicted. Therefore, CIN I were treated with physical therapy. In fact, if the patient is willing, have the conditions, is to allow them to carry out regular inspections and strict monitoring. CINII: CIN II patients should be carried out on physical therapy, such as freezing, electrocoagulation, laser, these treatments have their advantages and disadvantages, but the validity of the difference was not statistically significant. Their common disadvantage is that tissue samples can not be retained. Cervical loop electrosurgical excision procedure (LEEP) can also be used CINII treatment, the effect forward, but to retain tissue samples for pathological examination, will not miss a small part of undetected cervical carcinoma in situ or microinvasive carcinoma. To note the depth and width of cervical resection to meet the requirements. CINill: CINill itself includes severe dysplasia and carcinoma in situ, it should be palaces cervical resection, and except for invasive cancer. Older patients can also be directly with total hysterectomy. LEEP is only suitable for severe dysplasia and carcinoma in situ should not be used. LEEP treatment of carcinoma in situ, the recurrence rate is 29%, while the cold knife (CKC) The recurrence rate was only 65 after.

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