Liver cancer risk factors

By | April 18, 2012

The liver is the body's largest organ substantial, mostly in the upper abdomen and right quarter rib area, a small part of the season in the xiphoid and the left lower rib area, was tapped mode, fractal both lobes. In addition to the secretion of bile, the liver helps the digestion and absorption of fat, but also participate in various nutrients such as protein, carbohydrates, lipids, vitamin synthesis, conversion and storage processes, and detoxification, defense and other functions. Liver cancer is the most common malignant tumor in adults, about 75% of hepatocellular carcinoma, 13% for bile duct carcinoma, the other is a rare liver angiosarcoma and so on.
Risk factors for liver cancer: viral hepatitis, cirrhosis, aflatoxin, vinyl chloride, Mu dioxide compounds, contraceptive pills, the synthesis of steroids and other tablet formulations.
Liver cancer risk factors, (1) Viral Hepatitis: global data, hepatitis B, hepatitis C and hepatitis D is closely related with liver cancer. Of liver cancer patients, 900 / 0 has a background of hepatitis B infection, mostly on the basis of chronic hepatitis evolved. Have found that the integration of hepatitis B virus DNA and N-ras gene activation. Hepatitis C infection is often associated with blood transfusion related.
Has been developed in recent years, the hepatitis B vaccine can effectively prevent hepatitis B infection. Hepatitis B vaccine for all children to avoid inflammation of the liver caused by hepatitis B virus damage, thereby reducing the chronic hepatitis, cirrhosis and liver cancer incidence.
(2) cirrhosis of the liver:
Liver cirrhosis is the result of the formation of hardened nodules, often leading to liver cancer. Most patients with liver cirrhosis and hepatitis B, hepatitis C infection, some alcohol-related. Therefore, limited alcohol consumption to control the occurrence of cirrhosis and liver cancer is a major significance. Another reason is that excess iron absorption and liver related, which is a hereditary disease called hemochromatosis. Mainly due to the patient absorbed from food due to too much iron. The patients suffering from liver cancer risk 200 times higher than the average person. Early detection and aggressive treatment of this genetic disease can reduce the incidence of liver cancer.
(3) aflatoxin:
Aflatoxin is a strong carcinogen, which can cause liver cell DNA damage, mainly p53 gene damage, leading to abnormal cell growth and cancer. In tropical and subtropical areas, crops such as peanuts, wheat, soybeans, corn, rice and melons food is often easy to fungal contamination. People often eat this food is very easy to get liver cancer. In hot and humid areas, grain storage methods should be improved to prevent the grain was fungal contamination. While national authorities should establish appropriate prevention of food contamination and monitoring system.
Liver cancer risk factors, (4), vinyl chloride and oxide compounds Mu:
Long-term exposure to vinyl chloride and oxide compounds were male, it may lead to vascular sarcoma, but can also cause liver cholangiocarcinoma and hepatocellular carcinoma. Western countries have restrictions on the use and requirements to avoid contact with the food safety monitoring system should be established class of compounds harmful to the quality.
(5) contraceptive pills:
When birth control estrogen oral contraceptive pill can cause liver and benign tumors, called hepatic adenoma; this mild oral contraceptive pill can also increase the risk of hepatocellular carcinoma opportunities. However, this pill is now rarely used. Current use of estrogen and other hormones isomers, in combination, are carcinogenic is unclear.
(6) synthesis of steroids:
Synthesis of steroids is a male hormone, often taken by athletes to increase their exercise intensity, if the long-term use can increase the risk of hepatocellular carcinoma risk. Categories such as cortisone and dexamethasone has no such drawbacks.

Liver cancer risk factors, (7) monument:
In some parts of the world, drinking water containing high monument will increase the risk of hepatocellular carcinoma risk. Most liver cancer is through public health measures that avoid or reduce exposure to the risk factors to the prevention and control.

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