Cervical Cancer & HPV

Cervical Cancer, also known as Uterine Cancer, which is the bottom of the uterus, which is inside the vagina by placing a speculum, is caused in most cases by virus Human papillomavirus, or HPV. The subtypes of HPV virus that are related by 70% with cervical cancer are HPV viruses 16 and 18 while the remaining 30% of cervical cancers are related to HPV subtypes 31, 33, 35, 39, 45, 51, 52, 56, 58, 59, 68.

Cervical Cancer can be prevented by frequent gynecological check-ups as there are new TEST of HPV DNA techniques allow us to make an early diagnosis and certainty of infections caused by Human Papilloma Virus or HPV. HPV Test: the most used today are the PCR reaction (Polymerase Chain) and Hybrid Capture (Hybrid Capture) Both techniques have a high sensitivity (nearly 100% if the shot is done properly) to detect Human Papillomavirus or HPV and know that the subtype / or are infected when using the technique of Chain Reaction or PCR polymerase.

We remind you that you should not only conform perform a Pap smear and a colposcopy but is essential to make the HPV TEST.

Cervical Cancer affects women between 30 and 55 years of age, the average age between 40 and 45 years, statistical studies are from developed countries. In our population we can detect dysplastic lesions or cancer at much younger ages, mainly because of lack of access to regular checks from the beginning of relationships.

Prevention of Cervical Cancer.

For normal cells of the cervix undergo changes until abnormal cells become cancerous may take ten years or more, so it is very important to test and detect HPV in time.

What does detect the HPV virus in time?

Means the virus to enter cells from the cervix did not change the same to what is called LATENT PHASE. In the latent phase we know that HPV subtype infecting us and this is essentially whether the subtypes 16, 18 or any of those related to cancer, depending on the importance that we will treat the infection.

Remember that since the virus enters the cells HPV Cervical usually spend ten years before cancer develops, so if we make the diagnosis in time we have the possibility to prevent it completely.

Risk Factors for Cervical Cancer.

1. The lack of gynecological examinations every 6 months to 1 year precludes us early diagnosis and thus prevention.
2. Persistent infection of human papillomavirus (HPV), especially those at high risk (HPV 16, HPV 18, HPV 31, HPV 33, HPV 35, HPV 39, HPV 41, HPV 51, HPV 52, HPV 56, HPV 58 , HPV 59, HPV 68 and other less common) cause of most cervical cancers.
3. Other factors associated with cancer have to do with the body’s defenses. If these are low, we have more chances of getting infected the Human Papillomavirus or HPV and therefore more likely to get a cervical cancer.
4. Some diseases associated with weakened immune or immunodeficiency predisposes to contract cervical cancer such as the HIV virus infection, smoking, autoimmune diseases, immunosuppressive treatments, etc..
5. Also attributed a greater chance of getting cervical cancer in women who initiated sexual activity at an early age and multiple sexual partners.
6. Unfortunately there is more needy populations of cancer incidence of cervical cancer by lack of access to information, education, health systems and other saturated situations unwittingly bring with them diseases of all kinds such as in this case the virus infections human papillomavirus.
7. Some medications that contain hormones favor the persistence of viral infections by HPV.
8. Smoking Habit.
9. Recurrent genital infections
10. Couple with oncogenic HPV genital infection.

Symptoms of Cervical Cancer.

Are presented primarily as abnormal bleeding during or after intercourse, between periods, causing great discomfort for the patient who is affected in their daily activities.

Other symptoms that are associated with cervical cancer are excessive vaginal discharge with foul odor and sometimes in advanced cases. They may also appear aches and pains in pelvic and other body parts, if metastases or involvement of other organs beyond the little womb.

It is important to note that once these symptoms are present and Cancer treatment success is not as effective and is also the same aggressive, so we reemphasize the importance of a regular gynecological examinations including Pap colposcopy, and HPV TEST Microcolpohisteroscopía to be included in routine examinations as a precision tool for early diagnosis of Human Papilloma Virus or HPV.

What if I am diagnosed with invasive cervical cancer?

Staging is performed to see if this involved only the cervix or it has spread to other body parts such as the bladder, rectum, lung, etc.. Cervical Cancers are staged from 1 to 4 according to their degree of bodily invasion and based on staging is to plan treatment that usually consists of radical surgery, which involves the complete removal of the uterus, tubes, ovaries, part of the vagina and lymph nodes in the pelvis. Surgery is usually supplemented with other treatments such as chemotherapy and / or radiation, chemotherapy and radiotherapy simultaneously, to intravaginal radiotherapy called brachytherapy and a multidisciplinary treatment with various specialists to better containment and therapeutic results.

Currently there are advances in terms of surgeries that can be done for invasive cervical cancer.

These surgeries aim to be less aggressive for the patient and are combined with Laparoscopic Vaginal Surgery in trained hands is a valid and less invasive for the patient.

What if the patient wants to get pregnant and has a Cervical Cancer?

Currently there is a surgery called radical trachelectomy which is completely removed the cervix where the cancer, as long as it has not spread too much.

This technique preserves the uterine body, which is where the embryo is implanted during pregnancy, thus leaving the door open for women with cervical cancer may become pregnant. There are studies that report the evolution of pregnancy in women treated by this surgical procedure, especially in Canada where there were 50 pregnancies after having been operated by the technique of radical trachelectomy.

What are the chances of survival after treatment there?

1. Stage 1: 80 to 96% survival after 5 years.
2. Stage 2: 63 to 88% survival at 5 years.
3. Stage 3: 35 to 50% survival at 5 years.
4. Stage 4: 15 to 20% survival at 5 years.

Incidence.

In our country the incidence is higher than in developed countries there more prevalent in disadvantaged provinces such as Jujuy, Salta, Tucumán, Chaco, Formosa, Corrientes, Misiones and the Patagonian provinces.

Cervical Cancer is the second most common after breast in women.

Conclusions with respect to cervical cancer.

Now this is one of the few cancers that is preventable, being the key to preventing common gynecological checks including P apanicolaou, Colposcopy, Microcolpohisteroscopía and test for early detection of DNA including PCR (Chain Reaction Polymerase) or Hybrid Capture. Currently there are two preventive vaccine viral subtypes HPV 16, HPV 18 and both of them only against subtypes 16 and 18.

Failure to have Virus HPV vaccine will protect VIRUS HPV by 70% against cervical cancer and cancers related to HPV 16 and 18 VIRUS, which you can apply from 9 years of age although there many controversies that must be cleared by the treating professional.

CONSULTATIONS

“DNA testing for HPV Virus detection (PCR and Hybrid Capture). HPV in women and HPV in men. HPV TEST vs. Pap. Importance of early diagnosis of HPV. HPV and Cancer. Treatment of HPV. Relationship SIL HPV with low and high grade. Cervical Dysplasia and HPV. CIN 1, CIN 2, CIN 3, carcinoma in situ and its relationship with HPV. Different types of treatments for HPV Leep, Laser, cryosurgery, endocoagulation, Topicaciones, Interferon for the treatment of HPV. Other medical treatments for HPV. Relationship of HPV with cervical cancer, vagina, vulva, penis, anus, rectum, mouth. HPV in pregnant women, recommendations. HPV in the newly born. HPV Infection. vaccine to prevent HPV. ”