Lung pathology in major types of lung cancer

By | March 31, 2012

Shape from the naked eye, according to the site of tumor, gross type of lung cancer is divided into central, peripheral, and pleural diffuse type, in which the three previously common, pleural type less.
Lung pathology in major types of lung cancer 1. Central lung cancer (centre type) that the hilar type (hilar type) of lung cancer. Tumors occurred in the main bronchus, lobar bronchus and bronchial above paragraph. Tumor also extended along the bronchial wall and bronchial wall damage, peribronchial infiltration of lung tissue, the occurrence of bronchial lymph nodes, hilar lymph nodes, or even mediastinal lymph nodes enlarged lymph nodes and the formation of large primary tumor mass, its distal lung tissue occur more obstructive pneumonia. Common tumor necrosis gross specimen of the cut surface bleeding, and sometimes a small hole formed. Central lung cancer, 2 / 3 belong to order cancer. Early multi-cough, bloody sputum and other clinical symptoms, but often not timely treatment of patients can not seriously, when there is chest pain, hoarseness and other symptoms, the tumor had been violations of the surrounding lymph nodes and mediastinum, forming a large nodule or mass , loss of surgical treatment.
According to tumor morphology and growth patterns, the early and central two subtypes:
(1) tube type: This type of lung cancer tumors spread along the bronchial stalk membrane, leading to thickening of bronchial mucosa, despite infiltration of the bronchial wall, but still intact. Bronchial tumor confined within the lumen sudden, granular, papillary or polypoid. Extensive use of bronchoscopy, which greatly improves the rate of these early lesions.
(2) infiltrating the wall: tumor occurrence was part of the trachea wall thickening, bronchial wall damage not only cancer but also infiltrating the surrounding lung tissue, but not invading the hilar lymph nodes, etc.. Can be clearly shown on the cut surface of tumor bronchial lesions usually less than 2cm.
Lung pathology in the 2 main types of lung cancer. peripheral lung cancer (Peripheral type) in peripheral lung cancer in the following section of the small bronchi. Subpleural lung cancer in the surrounding. Single nodules were more common, but also for multiple nodules. Section of tumor nodules are pale, often accompanied by hemorrhagic necrosis, and the surrounding lung tissue boundaries more clearly, occasionally to be invasive in the bronchi.
According to the tumor volume, peripheral lung cancer were divided into ball and block type.
(1) ball: size is generally small, maximum diameter less than 3cm, clear boundaries with the surrounding lung tissue and bronchial no specific relationship between the tumor edge and sometimes lobulated.
(2) block type: a large spherical volume than the maximum diameter of more than 3cm, and the surrounding lung tissue is sometimes unclear boundaries, irregular mass, we can see varying degrees of necrosis.
Peripheral lung cancer, mostly cancer, more common in women. Early clinical symptoms was not obvious because, it is mostly accidental or physical examination finder. Easy to violations of the pleura, causing chest pain and malignant pleural effusion.
Lung pathology 3 main types of lung cancer. Mi Baptist lung cancer (diffuse type) and more diffuse type of lung cancer occurred in the bronchioles or alveoli, can affect both lungs. Most of the tumor occupied a large leaf or the entire large leaves, diffuse infiltration, it is also known as pneumonia, alveolar cell carcinoma, the lesion develops slowly, and clinical pulmonary fibrosis should be, or interstitial pneumonia be differentiated.
Lung pathology in 4 main types of lung cancer. Pleural lung (pleural type) primary tumor may have originated in the bronchioles, extensive infiltration of the pleura, the visceral and parietal pleura caused extensive adhesions, fusion, pleural involvement can be 1-2cm thick . Most of this type of poorly differentiated adenocarcinoma. Lung cancer diagnosis of pleural very difficult, not only difficult clinical diagnosis, pathological diagnosis is very difficult. General characteristics and chronic infection pleurisy, pleural mesothelioma and metastatic carcinoma is difficult to distinguish, the final diagnosis depends on histology and immunohistochemistry.
Central type of lung cancer, peripheral, diffuse, and pleural type, the former two common, diffuse rare type of pleural most rare.

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