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Personalizing cancer treatments for youngest patients

Precision medicine constitutes a different method of identifying best treatment options for patients. Instead of prescribing therapy based solely on the organ where the cancer originated, clinicians utilize genomic analysis for a more comprehensive approach. Through a rapid gene sequencing test, the tiniest details of a tumor biopsy are uncovered, sometimes revealing one or more mutations in the patient’s genes. It is the mutations themselves that can be targeted with new or existing drugs. …

Shut down of cell survival process found to influence fate of lung cancer tumors

Previous research from the laboratories of the senior authors Eileen P. White, PhD, associate director for basic science at the Cancer Institute of New Jersey and Joshua D. Rabinowitz, MD,PhD, professor of chemistry at Princeton University and Cancer Institute of New Jersey member, revealed that autophagy dependence is prevalent in cancers with Ras mutations. These mutations are activated in aggressive cancers with poor outcomes, such as lung…