Tag Archives: robert

Role of gene mutations involved in more than 75 percent of glioblastomas, melanomas

The research is published this month in the online journal PLOS ONE and is authored by Brad Chaires, Ph.D., John Trent, Ph.D., Robert Gray, William Dean, Ph.D., Robert Buscaglia, Shelia Thomas and Donald Miller, M.D., Ph.D. Telomerase is an enzyme largely responsible for the promotion of cell division. Within DNA, telomerase activation is a critical step for human carcinogenesis through the maintenance of telomeres. …

Diagnostic screening: Microwave imaging of the breast may be better and safer — ScienceDaily

A better, cheaper, and safer way to look for the telltale signs of breast cancer may be with microwaves, said Neil Epstein, a NSERC CREATE I3T postdoctoral fellow at the University of Calgary in Canada. Epstein and his colleagues–engineering professor Paul Meaney of Dartmouth College’s Thayer School of Engineering and Keith Paulsen, director of the Dartmouth Advanced Imaging Center and the Robert A. …

Injectable 3-D vaccines could fight cancer, infectious diseases

“We can create 3D structures using minimally-invasive delivery to enrich and activate a host’s immune cells to target and attack harmful cells in vivo,” said the study’s senior author David Mooney, Ph.D., who is a Wyss Institute Core Faculty member and the Robert P. Pinkas Professor of Bioengineering at Harvard SEAS. Tiny biodegradable rod-like structures made from silica, known as mesoporous silica rods (MSRs), can be loaded with biological and chemical drug components and then delivered by needle just underneath the skin. The rods spontaneously assemble at the vaccination site to form a three-dimensional scaffold, like pouring a box of matchsticks into a pile on a table…

How cells defend themselves against antibiotics, cytostatic agents

For the first time, the group led by Robert Tamp�, in collaboration with colleagues at the University of California in San Francisco, succeeded in determining the structure of an asymmetrical ABC transporter complex with the aid of a high-resolution cryo-electron microscope. “Over a period of five years, we have successfully implemented a number of innovative, methodological developments. …

Most Internet sources on prostate cancer disagree with expert panel’s recommendation — ScienceDaily

In an Internet search for the phrase “prostate cancer screening” on three main U.S. search engines, study researchers found that most sites appearing on the first results page recommended a patient-individualized approach to screening…

Shut down of cell survival process found to influence fate of lung cancer tumors

Previous research from the laboratories of the senior authors Eileen P. White, PhD, associate director for basic science at the Cancer Institute of New Jersey and Joshua D. Rabinowitz, MD,PhD, professor of chemistry at Princeton University and Cancer Institute of New Jersey member, revealed that autophagy dependence is prevalent in cancers with Ras mutations. These mutations are activated in aggressive cancers with poor outcomes, such as lung…