The researchers have not progressed that far yet. Although they have spent the past 20 years developing individual components and prototypes of biological computers, bio-computers today still differ significantly from their counterparts made of silicon, and bio-engineers still face several major obstacles…
“Exosomes derived from cells and blood serum of patients with breast cancer, have been shown to initiate tumor growth in non-tumor-forming cells when Dicer and other proteins associated with the development of miRNAs are present,” said Raghu Kalluri, M.D., Ph.D., chair of the department of cancer biology at MD Anderson. “These findings offer opportunities for the development of exosomes-based biomarkers and shed insight into the mechanisms of how cancer spreads.” Exosomes are small vesicles consisting of DNA, RNA and proteins enclosed in a membranes made up of two lipid layers…
MIT researchers have now developed a new way to model the effects of these genetic mutations in mice. Their approach, based on the genome-editing technique known as CRISPR, is much faster than existing strategies, which require genetically engineering mice that carry the cancerous mutations. “It’s a very rapid and very adaptable approach to make models,” says Thales Papagiannakopoulos, a postdoc at MIT’s Koch Institute for Integrative Cancer Research and one of the lead authors of the paper, which appears in the Oct…
MicroRNAs are small intracellular RNA molecules that regulate gene expression. Therefore, they play important roles in various normal processes of the human body, such as embryogenesis, and the regulation of cell viability. In addition, it is known that abnormal amounts of microRNA stimulate the onset and development of different diseases, such as cancer…
MicroRNAs are small intracellular RNA molecules that regulate gene expression. Therefore, they play important roles in various normal processes of the human body, such as embryogenesis, and the regulation of cell viability…
“According to research evidence, survival rates are considered equal,” explained dean Nancy Fahrenwald of the South Dakota State University College of Nursing. Working through the South Dakota Women’s Cancer Network, the South Dakota Comprehensive Cancer Control Program and seven cancer treatment centers in the state, Fahrenwald got responses from 1,093 breast cancer survivors who had been diagnosed in the last five years. To determine which of the nine independent variables tipped the scales toward mastectomy, she turned to associate professor Chris Saunders of the mathematics and statistics department. “The statistics were not meant to be innovative but to provide an answer that is robust and rigorous,” said Saunders, who used logistic regression to analyze the survey results…
Glioblastoma is the most common and deadliest form of brain cancer. The majority of these tumors – known as primary glioblastomas – occur in the elderly without evidence of a less malignant precursor. …
According to the American Cancer Society, prostate cancer is the second most common type of cancer in American men (behind skin cancer), and the second-leading cause of cancer death in men (after lung cancer). In 2014, more than 230,000 new cases of prostate cancer will be diagnosed…
According to the American Cancer Society, prostate cancer is the second most common type of cancer in American men (behind skin cancer), and the second-leading cause of cancer death in men (after lung cancer). In 2014, more than 230,000 new cases of prostate cancer will be diagnosed. …
In research published in the Early Edition of the Proceedings of the National Academy of Sciences, Prof. Ben-Jacob and researchers from Rice University and the University of Texas M.D…