Tag Archives: carolina

Approaches to pain assessment in cancer clinical trials

A new paper published by Cancer External Site describes approaches to pain measurement used in oncology clinical trials submitted to the U.S. Food and Drug Administration that are consistent with current FDA guidance principles. The purpose of the paper is to assist drug developers to include meaningful pain endpoints when designing cancer trials. "Measurement of pain and other symptoms is an essential part of cancer trials…

HPV associated with increased risk of HIV in men

The study, published online by the journal AIDS, was authored by Jennifer Smith, PhD, MPH, research associate professor with the Gillings School of Global Public Health and member of the UNC Lineberger Comprehensive Cancer Center, and Anne Rositch, PHD, MSPH, assistant professor with the University of Maryland School of Medicine. "These data from Kenya add to a mounting evidence showing a higher risk of HIV acquisition among individuals with genital HPV infections," said Smith. Men in the study with at least one occurrence of HPV infection faced double the risk of acquiring HIV, and those with three or more HPV infections had more than three times the risk of developing HIV. This pattern was consistent in both circumcised and uncircumcised men…

Injectable ‘smart sponge’ holds promise for controlled drug delivery

"We wanted to mimic the function of health beta-cells, which produce insulin and control its release in a healthy body," says Dr. Zhen Gu, lead author of a paper describing the work and an assistant professor in the joint biomedical engineering program at North Carolina State University and the University of North Carolina at Chapel Hill. …