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Laparoscopic surgery for bladder cancer leads to good long-term cancer control — ScienceDaily

Open radical cystectomy, or removal of the bladder though open surgery, is the treatment of choice for muscle invasive and high-risk non-muscle invasive bladder cancer; however, the surgery can lead to serious complications. Some hospitals are using minimally invasive procedures such as laparoscopic radical cystectomy, but there is little information on the effectiveness of these procedures for preventing cancer recurrence over the long term. To address this, the European Association of Urology (EAU)-section of Uro-technology has been building a large database of laparoscopic radical cystectomy procedures performed across Europe. …

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HPV vaccine, riskier sexual activity not linked, Canadian researchers say

There are concerns the vaccine, which guards against four types of the HPV shown to cause cervical cancer and anogenital warts, may give girls a false sense of security about contracting sexually transmitted infections (STIs) and lead them to engage in riskier sexual activity. “These findings suggest fears of increased risky sexual behaviour following HPV vaccination are unwarranted and should not be a barrier to vaccinating at a young age,” says Dr. Smith, the lead author on the study that was published in the Canadian Medical Association Journal. This study looked at a cohort of 260,493 girls, of whom about half (128,712) were eligible for Ontario’s publicly funded, school-based HPV vaccination program during the first two school years it was offered (2007-08 and 2008-09). …

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Expression of SIP1 protein indicates poor prognosis in pharyngeal cancer

Although pharyngeal squamous cell carcinoma (PSCC) is a rather rare disease, its incidence has been increasing over the past three decades, now accounting for 130,000 new cases and 80,000 cancer deaths worldwide. The prognosis is one of the poorest of all the head and neck squamous cell carcinomas and it has not improved to any significant extent, despite the availability of multimodal therapies. …

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Nonsmokers in automobiles are exposed to significant secondhand smoke

The nonsmoking passengers showed elevated levels of butadiene, acrylonitrile, benzene, methylating agents and ethylene oxide. This group of toxic chemicals is “thought to be the most important among the thousands in tobacco smoke that cause smoking-related disease,” said senior investigator Neal L. Benowitz, MD, a UCSF professor of medicine and bioengineering and therapeutic sciences and chief of the division of clinical pharmacology at San Francisco General Hospital and Trauma Center. …

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Risk stratification model may aid in lung cancer staging and treatment decisions

Lung cancer treatment and prognosis is critically dependent on accurate staging that takes into account the extent to which cancer has spread from the primary lung tumor to other locations. Examination of lymph nodes containing lung cancer cells that have spread can be done by surgical removal, historically the standard practice, or by using a less invasive more cost effective technique called endobronchial ultrasound-guided transbronchial needle aspiration (EBUS-TBNA). …

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Papillary thyroid carcinoma: New research

In the presentation “Impact of Radioactive Iodine on Survival in Papillary Thyroid Carcinoma,” Paritosh Suman, M.D. and colleagues from North Shore University Health System (Evanston, IL), explore the benefit of (RAI) treatment following surgery to remove the thyroid in patients with PTC, and whether survival benefit relates to tumor size. In a retrospective study of nearly 285,000 patients treated over 13 years, with a mean follow-up of 7 years, the authors found that 47% of patients had RAI therapy and it showed a small but statistically significant survival benefit regardless of the tumor size. Carrie Lubitz, M.D., M.P.H., Massachusetts General Hospital (Boston), and coauthors previously described a novel blood-based assay for detecting the V600E mutation in the BRAF gene in patients with melanoma…

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Latest research on thyroid cancer therapy

Renata Jaskula-Sztul, Ph.D., University of Wisconsin Medical School (Madison), and colleagues will deliver an oral presentation entitled “Targeted Delivery of a Novel Histone Deacetylase Inhibitor, AB3, Using Unimolecular Micelles to Improve Antitumor Effect in Medullary Thyroid Cancer.” MTC is a neuroendocrine tumor that accounts for 3-5% of thyroid cancers. …

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Prostate cancer risk reduced by sleeping with many women, but increased with many men, study finds

Marie-Elise Parent and Marie-Claude Rousseau, professors at university’s School of Public Health, and their colleague Andrea Spence, published their findings in the journal Cancer Epidemiology. The results were obtained as part of the Montreal study PROtEuS (Prostate Cancer & Environment Study), in which 3,208 men responded to a questionnaire on, amongst other things, their sex lives…

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